B7LUN9

PR
Gene name
ppc
Protein name
Phosphoenolpyruvate carboxylase
Names
PEPC, PEPCase
Species
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)
KEGG Pathway
efe:EFER_3807
EC number
4.1.1.31: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

68-139 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B7LUN9

Entry ID Method Resolution Chain Position Source
AF-B7LUN9-F1 Predicted AlphaFoldDB

No variants for B7LUN9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B7LUN9

No associated diseases with B7LUN9

2 regional properties for B7LUN9

Type Name Position InterPro Accession
active_site Phosphoenolpyruvate carboxylase, Lys active site 134 - 145 IPR018129
active_site Phosphoenolpyruvate carboxylase, His active site 537 - 549 IPR033129

Functions

Description
EC Number 4.1.1.31 Carboxy-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphoenolpyruvate carboxylase activity Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.

3 GO annotations of biological process

Name Definition
carbon fixation A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).
oxaloacetate metabolic process The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.
tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNEQYSALRS NVSMLGKVLG ETIKDALGEH ILDRVETIRK LSKSSRAGND ADRQELLTTL
70 80 90 100 110 120
QNLSNDELLP VARAFSQFLN LANTAEQYHS ISPKGEAASN PEVIARTLRK LKNQPDLSEA
130 140 150 160 170 180
TIKKAVESLS LELVLTAHPT EITRRTLIHK MVEVNTCLKQ LDNKDLADYE RNQLMRRLRQ
190 200 210 220 230 240
LIAQSWHTDE IRKQRPSPVD EAKWGFAVVE NSLWQGVPNY LRELNEQLEE NLGFKLPVDF
250 260 270 280 290 300
VPVRFTSWMG GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDIQVLVSEL SMVEATPELL
310 320 330 340 350 360
ALVGEEGAAE PYRYLMKNLR SRLMTTQAWL EARLKGQKLP KPEGLLTQNE ELWEPLYACY
370 380 390 400 410 420
QSLQACGMGI IANGDLLDTL RRVKCFGVPL VRIDIRQEST RHTEALGELT RYLGIGDYES
430 440 450 460 470 480
WSEADKQAFL IRELNSKRPL LPRNWQPSAE TREVLDTCQV IAEAPQGSIA AYVISMAKTP
490 500 510 520 530 540
SDVLAVHLLL KEAGIGFAMP VAPLFETLDD LNNANDVMTQ LLNIDWYRGL IQGKQMVMIG
550 560 570 580 590 600
YSDSAKDAGV MAASWAQYQA QDALIKTCEK AGIELTLFHG RGGSIGRGGA PAHAALLSQP
610 620 630 640 650 660
PGSLKGGLRV TEQGEMIRFK YGLPEITVSS LSLYTGAILE ANLLPPPEPK ESWRRIMDEL
670 680 690 700 710 720
SVISCDVYRG YVRENKDFVP YFRSATPEQE LGKLPLGSRP AKRRPTGGVE SLRAIPWIFA
730 740 750 760 770 780
WTQNRLMLPA WLGAGTALQK VVEDGKQSEL ETMCRDWPFF STRLGMLEMV FAKADLWLAE
790 800 810 820 830 840
YYDQRLVAKE LWPLGKELRN LLEEDIKVVL AIANDSHLMA DLPWIAESIQ LRNIYTDPLN
850 860 870 880
VLQAELLHRS RLTEQNGKEP DPRVEQALMV TIAGVAAGMR NTG