B7LN23

PR
Gene name
rlmC
Protein name
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC
Names
23S rRNA(m5U747)-methyltransferase
Species
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)
KEGG Pathway
efe:EFER_1002
EC number
2.1.1.189: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

29-111 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B7LN23

Entry ID Method Resolution Chain Position Source
AF-B7LN23-F1 Predicted AlphaFoldDB

No variants for B7LN23

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B7LN23

No associated diseases with B7LN23

2 regional properties for B7LN23

Type Name Position InterPro Accession
active_site RNA methyltransferase TrmA, active site 307 - 338 IPR030390
conserved_site RNA methyltransferase TrmA, conserved site 357 - 367 IPR030391

Functions

Description
EC Number 2.1.1.189 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
iron ion binding Binding to an iron (Fe) ion.
rRNA (uridine-C5-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQCALYDAGR CRSCQWITQL IPEQLSAKTA DLKNLLADFS VEEWCESVSG PEQGFRNKAK
70 80 90 100 110 120
MVVSGSVEKP LLGMLHRDGT PEDLCDCPLY PSSFAPVFAA LKPFIARAGL TPYNVARKRG
130 140 150 160 170 180
ELKYILLTES QSDGGMMLRF VLRSETKLAQ LRKALPWLQE QLPQLKVITA NIQPIHMAIM
190 200 210 220 230 240
EGETEIYLTE QQALAERFND VPLWIRPQSF FQTNPVVASQ LYATARDWVR QLPVKHMWDL
250 260 270 280 290 300
FCGVGGFGLH CATPDMQLTG IEIAPEAIAC AKQSAAELGL TRLQFQALDS TQFATTQGEV
310 320 330 340 350 360
PELVLVNPPR RGIGKPLCDY LSTMAPRFII YSSCNAQTMT KDIRELSGYR IERVQLFDMF
370
PHTAHYEVLT LLVKQ