B7K8U6

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Gloeothece citriformis (strain PCC 7424) (Cyanothece sp. (strain PCC 7424))
KEGG Pathway
cyc:PCC7424_2889
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

163-234 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B7K8U6

Entry ID Method Resolution Chain Position Source
AF-B7K8U6-F1 Predicted AlphaFoldDB

No variants for B7K8U6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B7K8U6

No associated diseases with B7K8U6

3 regional properties for B7K8U6

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 278 - 287 IPR020557
domain Fumarate lyase, N-terminal 10 - 303 IPR022761
domain Argininosuccinate lyase, C-terminal 367 - 435 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTEKKTWSDR FEGSLHPAIA YFNASIEFDI ELIEYDLTGS IAHAKMLAHT GIISETEAQQ
70 80 90 100 110 120
LVTGLEQIRA EYREGQFNPG IDQEDVHFAV ERRLTEIIGD VGKKLHTARS RNDQVGTDIR
130 140 150 160 170 180
LYLRDQIDQI RGQIREFQQV LLDHAQNHVE TLIPGYTHLQ RAQPVSLAHH LLAYFHMAQR
190 200 210 220 230 240
DWERLGEIRK RTNISPLGSG ALAGTTFPID RHYSAQLLQF EGVYPNSLDG VSDRDFAIEF
250 260 270 280 290 300
LNAASLIMVH LSRLSEEMIL WSSQEFSFIT LTDSCATGSS IMPQKKNPDV PELIRGKTGR
310 320 330 340 350 360
VFGHLQGLLV LMKGLPLAYN KDLQEDKEAL FDGVKTVKGC LEAMTILLSE GIKFKTERLT
370 380 390 400 410 420
QAVNEDFSNA TDVADYLAAR GVPFREAYNL VGKVVKTSLA AGKLLKDLTL DQWKELHPAF
430 440 450 460
EADIYEAIAP SQVVAARNSY GGTGFKQVRQ AILTAKTLLE SN