B7ICY9

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Thermosipho africanus (strain TCF52B)
KEGG Pathway
taf:THA_1422
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

787-856 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B7ICY9

Entry ID Method Resolution Chain Position Source
AF-B7ICY9-F1 Predicted AlphaFoldDB

No variants for B7ICY9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B7ICY9

No associated diseases with B7ICY9

8 regional properties for B7ICY9

Type Name Position InterPro Accession
domain Helicase, C-terminal 456 - 620 IPR001650
domain SecA DEAD-like, N-terminal 1 - 424 IPR011115
domain SecA Wing/Scaffold 610 - 806 IPR011116
domain SecA, preprotein cross-linking domain 268 - 380 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 79 - 287 IPR014001
domain SecA motor DEAD 1 - 612 IPR014018
conserved_site SecA conserved site 522 - 537 IPR020937
domain SecA, C-terminal helicase domain 442 - 582 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKLFDKNERV IKKYWKKVNK INKINLESKN LTELINSLKT IKENITPENI DEYIPEVFAI
70 80 90 100 110 120
VREVSKRVIG LRPFDVQLIG AMVLHEGKVA EMKTGEGKTL VATMPVVLNA LLGKGVHLVT
130 140 150 160 170 180
VNDYLAKRDA MWMGPIYLAL GLRVGVINTQ NKSYEVIWKN EELAKKALNE NLSVWPQGFN
190 200 210 220 230 240
GEFLEDEAKN KEALEAYQVE LKEISRKEAY ECDITYGTNT EFGFDYLRDN LVIDLEDRVQ
250 260 270 280 290 300
RGHFYAIVDE VDSILIDEAR TPLIISGPSK TKASDYIRFN QIAKKLVKDK HFTIDEQKKS
310 320 330 340 350 360
VILTDEGIEY IEKLLNIENL YDPEHVNKMY FLLNALKAHY LFKKDVDYII HNGEIVIVDE
370 380 390 400 410 420
FTGRLLPGRR YSGGLHQAIE AKEGVKIKEE SVTYATITYQ NYFRMYEKLS GMTGTAKTEE
430 440 450 460 470 480
EEFKQIYGME VVVIPTHKPM IRIDRDDLIY RTEDEKFEAV VKEIKKRYEK GQPVLVGTTS
490 500 510 520 530 540
IEKSERLSKM LSKEKIPHNV LNAKHHEKEA QIVALAGQKG SVTIATNMAG RGTDIKLGPG
550 560 570 580 590 600
VKELGGLLII GTERHESRRI DNQLRGRAGR QGDPGESIFF LSLEDDIIRI FGGEKLEKIM
610 620 630 640 650 660
NLVKIEKGEP IYHPMLTKLI ERVQKKVESI NFGIRKNLLQ MDTVLDTQRR AIYSYREYLL
670 680 690 700 710 720
SGNIDEHFND AIDDFIERRL EEFCEKGVCN VEEIKESLKI LNISLDKLPD TRNELKEYLK
730 740 750 760 770 780
NLLMEKFENK KKELGEDFPK IGKFIALRVI DENWRQYLEE VEHVKEAVSL RAYGQKDPIL
790 800 810 820 830 840
EFKKETFRMF DEMMAKIFEQ TIIYTLNIRK ITDEAEKESE NELKKINTQH DEFTLVNRKE
850
RRVAEKKGKK KLKVKR