B6YUR8
Gene name |
tgtA |
Protein name |
tRNA-guanine(15) transglycosylase |
Names |
7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase |
Species |
Thermococcus onnurineus (strain NA1) |
KEGG Pathway |
ton:TON_0617 |
EC number |
2.4.2.48: Pentosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B6YUR8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B6YUR8-F1 | Predicted | AlphaFoldDB |
No variants for B6YUR8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B6YUR8 | |||||
No associated diseases with B6YUR8
5 regional properties for B6YUR8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PUA domain | 505 - 579 | IPR002478 |
| domain | tRNA-guanine(15) transglycosylase-like | 6 - 337 | IPR002616 |
| domain | Uncharacterised domain CHP00451 | 485 - 575 | IPR004521 |
| domain | tRNA-guanine transglycosylase, patch-forming domain C2 | 435 - 503 | IPR029402 |
| domain | tRNA-guanine(15) transglycosylase, C1 domain | 357 - 426 | IPR032729 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.2.48 | Pentosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| pentosyltransferase activity | Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA modification | The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVEFKFEVKA | RDAAGRIGKL | EVNGKKIETP | AIMPVINPKQ | LTVTPKELKE | MGFGIIITNS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YIIYKTPELR | EKALEVGIHR | LLDYDGIIEV | DSGSFQLMRY | GGVDVTNREI | VEFQERIGVD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IGTFLDIPTP | PDAPREKAEE | DLRITLERAK | EAEEIKGIAM | NAAVQGSTYP | DLRTYAARKL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SEMNFEIHPI | GAVVPLMESY | RYRDLVDVVI | ASKQGLRSDR | PVHLFGAGHP | MIFALAVAMG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IDLFDSASYA | LYAKDDRYLT | PEGTKHLSEL | EYFPCSCPVC | SRYTPRELRE | MPKEERTRLL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ALHNLWVIRE | ELNRVKQAIK | EGELWRLVDE | RARSHPKLYA | AYKRLLEYQD | YLEKNEPITK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ASAFFKVSEE | SLKWPIVQRA | KARAERVKAK | FPETINHPIF | GEIPKYLSLS | YPFAQSEGEE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DFTIEKPGKR | EVRNYVMAVA | EYQFGEGTRE | AFKDAFVELS | RKTGMPRQIK | AKGKHLATFR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AEDGLLTLGI | EGAKRLHEIL | PFPRMRVVVD | EDAEPFARKG | KNVFAKFVID | ADENIRPYDE |
| 550 | 560 | 570 | |||
| VLIVNRNDEL | LATGQTLLNG | RELKLFQSGL | AVKVRRGVEK |