B6QP49
Gene name |
PMAA_048060 |
Protein name |
Mannitol-1-phosphate 5-dehydrogenase |
Names |
M1PDH, MPD, MPDH |
Species |
Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) (Penicillium marneffei) |
KEGG Pathway |
tmf:PMAA_048060 |
EC number |
1.1.1.17: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B6QP49
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B6QP49-F1 | Predicted | AlphaFoldDB |
No variants for B6QP49
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B6QP49 | |||||
No associated diseases with B6QP49
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.1.17 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mannitol-1-phosphate 5-dehydrogenase activity | Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mannitol metabolic process | The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGKKAIQFGG | GNIGRGFVAE | FLHESGYEVV | FIDVVPQVIE | SLNKNKSYEV | TEISEEGEKT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KTITNYRALS | SKTQEPEVVK | EIATADVVTC | AVGPNILKFI | APVIAKGIDA | REEGLPPIAV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IACENAINAT | DALRGYIEEH | LDKSRLDTLP | KRARFANSAI | DRIVPTQPEH | AGLNVRIEKF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YEWAVEQTPF | GEYGHPDISA | IHWVDHLEPY | IERKLFTVNT | GHATAAYYGY | KAGKKTIHEA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MAEETIHKAV | HAALDETASL | IISKHEITEQ | EQKEYVKTII | SRISNPYLED | VVERVGRAPL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RKLSRKERFI | GPAAQLAERG | MKFDALLGSI | EKALQFQNVK | GDDESTELAK | ILSEKTAAEA |
| 370 | 380 | ||||
| TQQITGLETD | HPLYQPVLKV | VEKVQSVSK |