B6QHL4

PR
Gene name
mef1 (PMAA_094650)
Protein name
Elongation factor G, mitochondrial
Names
EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1
Species
Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) (Penicillium marneffei)
KEGG Pathway
tmf:PMAA_094650
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

38-109 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B6QHL4

Entry ID Method Resolution Chain Position Source
AF-B6QHL4-F1 Predicted AlphaFoldDB

No variants for B6QHL4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B6QHL4

No associated diseases with B6QHL4

2 regional properties for B6QHL4

Type Name Position InterPro Accession
domain Sulphate adenylyltransferase catalytic domain 174 - 387 IPR024951
domain ATP-sulfurylase PUA-like domain 4 - 164 IPR025980

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome.

1 GO annotations of biological process

Name Definition
mitochondrial translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVRPAQVRAF SGLARSATST RLIPSQCQNA LRCASLPGSR LSALPLRATQ ITSSPLRKWH
70 80 90 100 110 120
QIRNASAAAT ATLAEQAAAD PEGLSQEEII SNIDAEEWKR ISKVRNIGIA AHIDSGKTTA
130 140 150 160 170 180
TERVLFYTGR INSIHEVRGR DSVGAKMDSM DLEREKGITI QSAATFCDWV KKEDGKEEKY
190 200 210 220 230 240
HFNLIDTPGH IDFTIEVERA LRVLDGAVMI LCAVSGVQSQ TITVDRQMKR YNVPRISFVN
250 260 270 280 290 300
KMDRMGANPF KAIDQINSKL RLPAAAVQVP IGAEDEFQGV VDLIRMKAIY NEGPRGEVIV
310 320 330 340 350 360
EKDEIPEHLK PVAEERRRIL IETLADVDDE IAEIFLDERE PTNEQIKDAI RRATIALKFT
370 380 390 400 410 420
PVFMGSALAD KSIQPMLDGV CDYLPNPSEV TNLALDQKRK EAQVKLLPYG SEPFVGLAFK
430 440 450 460 470 480
LEESNFGQLT YIRVYQGTLR KGANVFNARN DKKVKVPRIV RMHSNEMEEV QEIGAGEICA
490 500 510 520 530 540
VFGVDCASGD TFTDGQLAYT MSSMFVPEPV ISLSIKPKNN KDSANFSKAM ARFQREDPTF
550 560 570 580 590 600
RVSYDAESEQ TIISGMGELH LDIYVERMRR EYKVDCETGQ PQVAYRETIG RRVEFDHLLK
610 620 630 640 650 660
KQSGGPGDYA RVVGWMEPSD SLEENKFEEQ IVGGAISEKF LFACEKGFNL ATEKGPLIGH
670 680 690 700 710 720
KVLGTKMVIN DGATHMTDSS EMSFKNATQQ AFRKAFMESQ PHVLEPLMKT VVTAPIEFQG
730 740 750 760 770 780
DVIGLLNKRN ATINDSEIGV DEFTVYADCS LNGMFGFSSH LRAATQGKGE YTMEFSHYEK
790 800
APGQLQKELV QKYLKAQADR HKK