Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B6KG46
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B6KG46-F1 | Predicted | AlphaFoldDB |
No variants for B6KG46
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B6KG46 | |||||
No associated diseases with B6KG46
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| positive regulation of G2/M transition of mitotic cell cycle | Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle. |
| protein homooligomerization | The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. |
| regulation of cell differentiation | Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. |
| regulation of gene expression | Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGKKRRKHDG | SGSSRSPSPD | RIREARNPSQ | AEVAGFRAPP | SGKPAMTVKQ | LREERQKLLH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EHFGYSNTNN | PFGDRLLAEP | FVWKKKNQLL | QAAGQKGKTT | VAALIHSSKS | KVQEIENVKR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RREEREKEEE | LMQQQREELQ | REKEREHYEE | YAQKEELFHR | SNQLKKTEIR | LEQNRAQLID |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LIVKGLRIIK | GERFEKMDVL | PGPPHEVLET | YKNEPVTVAM | LEDLIADVKL | HIDVDTTVVD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ADFQDFWKSL | LVLAREALER | AKKRKDVLDQ | LARNSSPQMA | AEAAAQLADT | VCPQIRDADT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GIVLSVAHEI | EGLLGGKSAA | ELDELEAQIR | SKFEEEDIDV | AYWEGILNKI | PSFRARAVCL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QTWHMMTQSA | ADAEREMARE | KALKEEEEAK | AARAKGEELE | GLLLEEADAR | KLARAQQIKQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DAIKVARSVE | KDVNPNADGS | FSPELEPYDE | GEVPPPVRGP | YSPQLWPFDE | FRHAEILAPD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DDEDRRAILK | KTLIQKERLK | RAGLEEDPEP | TPEAAENDAS | LDVLDPAAKV | TTYEEFVKKE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KKNLEADEEV | MASSSEHKLT | MHYTWEEKYR | PRKPRFFNRV | KTGYSWNKYN | TTHYDHDNPP |
| 610 | 620 | 630 | 640 | 650 | 660 |
| PKVVQGYKFN | IFYPDLIDKT | KAPTWFLEPS | DTPDTVIIRF | HAGPPYEDIA | FKILNQEWQL |
| 670 | 680 | ||||
| ERFRGFRNVF | DRGIMQLYFS | FKRYIYRR |