B6JAC3

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Afipia carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5) (Oligotropha carboxidovorans)
KEGG Pathway
ocg:OCA5_c04270
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

846-941 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B6JAC3

Entry ID Method Resolution Chain Position Source
AF-B6JAC3-F1 Predicted AlphaFoldDB

No variants for B6JAC3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B6JAC3

No associated diseases with B6JAC3

8 regional properties for B6JAC3

Type Name Position InterPro Accession
conserved_site SEC-C motif 921 - 939 IPR004027
domain SecA DEAD-like, N-terminal 6 - 389 IPR011115
domain SecA Wing/Scaffold 655 - 865 IPR011116
domain SecA, preprotein cross-linking domain 228 - 345 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 247 IPR014001
domain SecA motor DEAD 3 - 656 IPR014018
conserved_site SecA conserved site 512 - 527 IPR020937
domain SecA, C-terminal helicase domain 407 - 626 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIGALARKIF GSANDRRVKG YQARVDAINA MEPEIAALSD EALKARTAEF KQQLASGKTL
70 80 90 100 110 120
DDILVPAFAT VREAAKRTLG QRHFDVQLIG GMVLHEGDIA EMKTGEGKTL VATLAVYLNA
130 140 150 160 170 180
LTGRGVHVVT VNDYLAKRDA EWMSQVYSFL GLTTGIIIHG LDDPERQAAY ACDITYGTNN
190 200 210 220 230 240
EFGFDYLRDN MKYRLEDMVQ RDHVFAIVDE VDSILIDEAR TPLIISGPLD DRSEFYNTID
250 260 270 280 290 300
TFIPKLEPAD YEIDEKQRTV TLTEGGMEKL EQMLREAGLL KGESLYDIEN VSVVHHVNQA
310 320 330 340 350 360
LRAHRLFTRD KDYIVRDGEV VIIDEFTGRM MPGRRYSEGL HQALEAKEHQ PVQPENQTLA
370 380 390 400 410 420
SITFQNYFRM YEKLGGMTGT AATEADEFFD IYKLEVLEIP TNLPIARLDE DDEVYRSSRE
430 440 450 460 470 480
KYAAILAEIE RANGRMQPVL VGTASIEKSE VLADFLKEHG YKQIDFANPK SMAKLYDAAR
490 500 510 520 530 540
AGKPSKLFAV LNARFHEQEA YIVAEAGVPG AITIATNMAG RGTDIKLGGS LEMRAAAATA
550 560 570 580 590 600
GIEDEAEKQK IVEGIKADIE KFKEMVLAAE ETVELEPGKP GGKTIKKPGG LYIIGSERHE
610 620 630 640 650 660
SRRIDNQLRG RAGRQGDPGR TKFYLSLDDD LMRIFGSDRL EGMLQRLGLK EGEAIIHPWI
670 680 690 700 710 720
NKALEKAQQK VEARNFDIRK NLLKYDDVQN DQRKVIFEQR IDLMRDQNVS ETVTDMRHTL
730 740 750 760 770 780
IEGLVAKHIP EHAYPEQWDV SGLREELQRV IGLDLPVEDW AKEEGIADEE MLSRLQQRVD
790 800 810 820 830 840
EHMAAKSAQW GPEVMRYVEK TILLQTLDHL WREHLIMLDH LRQVIGLRGY GQRDPLQEYK
850 860 870 880 890 900
SEAFELFESL ISHMREAVTA QLMRVEIVPP DEQPPMPAME AHKLDPNTGE DQVAQAQSGL
910 920 930 940
APVAPAKRDP ANPATWGKVG RNEDCPCGSG RKFKHCHGRY A