B6J4L3

PR
Gene name
gpsA
Protein name
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Names
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
Species
Coxiella burnetii (strain CbuK_Q154) (Coxiella burnetii (strain Q154))
KEGG Pathway
cbc:CbuK_1746
EC number
1.1.1.94: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

113-188 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B6J4L3

Entry ID Method Resolution Chain Position Source
AF-B6J4L3-F1 Predicted AlphaFoldDB

No variants for B6J4L3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B6J4L3

No associated diseases with B6J4L3

2 regional properties for B6J4L3

Type Name Position InterPro Accession
domain Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal 181 - 322 IPR006109
domain Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal 8 - 161 IPR011128

Functions

Description
EC Number 1.1.1.94 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
glycerol-3-phosphate dehydrogenase complex An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.

2 GO annotations of molecular function

Name Definition
glycerol-3-phosphate dehydrogenase [NAD+] activity Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.

5 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
glycerol-3-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol.
glycerol-3-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.
glycerophospholipid metabolic process The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEPFKHPIAI LGAGSWGTAL ALVLARKGQK VRLWSYESDH VDEMQAEGVN NRYLPNYPFP
70 80 90 100 110 120
ETLKAYCDLK ASLEGVTDIL IVVPSFAFHE VITRMKPLID AKTRIAWGTK GLAKGSRLLH
130 140 150 160 170 180
EVVATELGQV PMAVISGPSL ATEVAANLPT AVSLTSNNSQ FSKDLIERLH GQRFRVYKND
190 200 210 220 230 240
DMIGVELCGS VKNILAIATG ISDGLKLGSN ARAALITRGL TEMGRLVSVF GGKQETLTGL
250 260 270 280 290 300
AGLGDLVLTC TDNQSRNRRF GLALGEGVDK KEAQQTIGQA IEGLYNTDQV HALAQKHAIE
310 320 330
MPLTFQVHRI LHEDLDPQQA VQELLERSPK AE