B5YK82
Gene name |
hemE |
Protein name |
Uroporphyrinogen decarboxylase |
Names |
UPD, URO-D |
Species |
Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87) |
KEGG Pathway |
tye:THEYE_A0806 |
EC number |
4.1.1.37: Carboxy-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B5YK82
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B5YK82-F1 | Predicted | AlphaFoldDB |
No variants for B5YK82
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B5YK82 | |||||
No associated diseases with B5YK82
1 regional properties for B5YK82
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Uroporphyrinogen decarboxylase (URO-D) | 2 - 333 | IPR000257 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.1.1.37 | Carboxy-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| uroporphyrinogen decarboxylase activity | Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| heme biosynthetic process | The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. |
| protoporphyrinogen IX biosynthetic process | The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKEAFLKACR | GIRTDYTPVW | FMRQAGRYMP | EYQKLRQKYD | FLTMCKTPEI | AAEVTLQPVK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VLGVDAAILF | SDILIPLEAM | GLKIEFIDDK | GPQVLPNIRT | VADLEILGEL | NLEKIGFVFD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AIRILINELN | VPLIGFAASP | FTLATYVIEG | GSTKEFVNTK | RFMFLEPEGF | HKLMSLFTKA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TQKYLNEQIR | AGVHAVQIFD | TWAGILSPFD | YESFVKPYVK | RLIESLKTVP | VIYFSSNTAG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LINHLKELNA | DVLSIDWRID | IKDATDLLKN | KPLQGNLDPL | TLLGSDEELF | KRVEKVLIGA |
| 310 | 320 | 330 | |||
| RGAKSHIFNL | GHGVNINTSV | DKLKKLVDFV | HEFKFMED |