B5YJZ3

PR
Gene name
hemA
Protein name
Glutamyl-tRNA reductase
Names
GluTR
Species
Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
KEGG Pathway
tye:THEYE_A0716
EC number
1.2.1.70: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

285-410 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B5YJZ3

Entry ID Method Resolution Chain Position Source
AF-B5YJZ3-F1 Predicted AlphaFoldDB

No variants for B5YJZ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B5YJZ3

No associated diseases with B5YJZ3

3 regional properties for B5YJZ3

Type Name Position InterPro Accession
conserved_site Flavodoxin, conserved site 5 - 21 IPR001226
domain Flavodoxin/nitric oxide synthase 3 - 172 IPR008254
domain Flavodoxin domain 4 - 153 IPR026816

Functions

Description
EC Number 1.2.1.70 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
glutamyl-tRNA reductase activity Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH.
NADP binding Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.

1 GO annotations of biological process

Name Definition
protoporphyrinogen IX biosynthetic process The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSLIVIGLNH KTAPVEIREK IAFNSKEAIK EALKELIQRE GIGEVVIIST CNRVEIYVYT
70 80 90 100 110 120
ANVSDLKREN QVEETIKAFL SNFHNIEIGE FENYLYVYKD TEAVEHLFKV ASSLDSMIVG
130 140 150 160 170 180
EPQITGQVKE SYEIALSERT TSLILNYLMN RALFTAKRVR NETRIGENPV SVSYAAVGLI
190 200 210 220 230 240
KKVFDELSKK SILLVGAGEM AELALRHLIG SGIKNVYLTN RTFQRAEEIA KEFNGVAVPF
250 260 270 280 290 300
GNLKEQLVKT DIVICSTGAP HYVITEQMLK EVMPLRKHKP IFFIDISVPR NVDPACNELD
310 320 330 340 350 360
NVYLYNIDDL QDVVDSNILE RKKEAEKALS IVQEETEKFF QWLNSLESVP VIVSIRNKAE
370 380 390 400 410 420
QVRQEEIEKF KAKYKDLPPE LINSIDYLTQ SIINKIMHSP TVALKNNCEN KEILIFSARR
LFGLDSEEE