B5YHT8
Gene name |
infB |
Protein name |
Translation initiation factor IF-2 |
Names |
|
Species |
Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87) |
KEGG Pathway |
tye:THEYE_A1884 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B5YHT8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B5YHT8-F1 | Predicted | AlphaFoldDB |
No variants for B5YHT8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B5YHT8 | |||||
No associated diseases with B5YHT8
5 regional properties for B5YHT8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 250 - 419 | IPR000795 |
| domain | Small GTP-binding protein domain | 255 - 409 | IPR005225 |
| domain | Translation initiation factor IF-2, N-terminal | 176 - 226 | IPR006847 |
| domain | Translation initiation factor IF- 2, domain 3 | 526 - 640 | IPR023115 |
| domain | Translation initiation factor IF-2, domain II | 425 - 520 | IPR044145 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| translational initiation | The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTKAVRSIE | LARELGVKPL | EIVKFIEKIR | NIQFKKGTTN | IKVEPDEIDK | IIQHFKKEAK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LEKIKEKEEK | PVELKKTEEI | KELEEKKPIT | PKIIEEEIKE | EEELQLPGRF | RREISFEKIE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KIKPKPVPTK | IPPKKFEPKK | WLDIKEQKKV | KDKNKKEEPA | VTPSTAPRKK | SIKIEEGTTV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KEFAELIGQK | VPDVIKKFME | LGYMPTINQP | VDIDAAQLVA | ESFGIKVEFS | QTQELDIIEE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VEDSPELLQP | RPPIVTVMGH | VDHGKTSLLD | AIRKTKVTEQ | EAGGITQHIG | AYKVTLQGKD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ITFLDTPGHE | AFTALRARGA | KVTDIVVLVV | AADDGVMPQT | IEAINHAKAA | NVPIVVAVNK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IDKPEANPQR | VRTQLSDYGV | IPEEWGGQNI | FVDISAKKRI | GIENLLEMIA | LQAEIMELKA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NPNKPARGTI | IESRLDKGRG | PVATVIVQNG | TLRIGDAFVA | GVTYGKVRAI | IDDTGKRINE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| APPSTPVEVV | GFEEVPQAGD | SFTVVEDERI | ARQIANTRAQ | KKRLAEMQKA | QRLTLQDLYE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KIKEGEVKEL | NLVIKGDVQG | SVEALKKAVE | DITHPEIKVK | VIHTGVGGIT | ESDVNLAATA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NAIIIGFNVR | PETKAQDLAE | QLGVDIKLYS | IIYEVIDDVK | KALQGMLEPE | IKERVIGRAE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VRAVFKISKI | GTVAGCYVLN | GTISRASDGV | RVIRDNIVVY | EGKISSLKRF | KEDVREVQAG |
| 730 | 740 | 750 | |||
| YECGITIENF | NDIKEGDILE | NYVLEKVPVK | GL |