B5XSX4

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Klebsiella pneumoniae (strain 342)
KEGG Pathway
kpe:KPK_0546
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

79-154 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B5XSX4

Entry ID Method Resolution Chain Position Source
AF-B5XSX4-F1 Predicted AlphaFoldDB

No variants for B5XSX4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B5XSX4

No associated diseases with B5XSX4

7 regional properties for B5XSX4

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 395 - 564 IPR000795
domain Small GTP-binding protein domain 399 - 554 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 52 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 320 - 370 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 57 - 95 IPR013575
domain Translation initiation factor IF- 2, domain 3 671 - 785 IPR023115
domain Translation initiation factor IF-2, domain II 571 - 664 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDVTIKALA SEIQTSVDRL IQQFADAGIR KSADDSVTAQ EKQTLLTHLN REHGSAPDKL
70 80 90 100 110 120
TLQRKTRSTL NIPGTGGKSK SVQIEVRKKR TFVKRDPQEA ERLAAEEQAQ REAEEQARRE
130 140 150 160 170 180
AEEAAKREAQ LKAEREAAEQ AKREVADKAK REAAEKDKVS NQHTDEMTKT AQAEKIRREN
190 200 210 220 230 240
EAAELKRKSE EEARRKLEEE ARRVAEEARR MAEENEKNWS ETSDSPEDSS DYHVTTSQHA
250 260 270 280 290 300
RQAEDDNDRE VEGGRGRSRS SKAARPAKKG NKHAESKADR EEARAAVRGG KGGKHRKGSA
310 320 330 340 350 360
LQQGFQKPAQ AVNRDVIIGE TITVGELANK MAVKGSQVIK AMMKLGAMAT INQVIDQETA
370 380 390 400 410 420
QLVAEEMGHK VILRRENELE EAVMSDRDTG AAAEPRAPVV TIMGHVDHGK TSLLDYIRST
430 440 450 460 470 480
KVASGEAGGI TQHIGAYHVE TDNGMITFLD TPGHAAFTSM RARGAQATDI VVLVVAADDG
490 500 510 520 530 540
VMPQTIEAIQ HAKAAQVPVV VAVNKIDKPE ADPDRVKNEL SQYGILPEEW GGESQFVHVS
550 560 570 580 590 600
AKAGTGIDDL LDAILLQAEV LELKAVRNGM ASGAVIESFL DKGRGPVATV LVREGTLHKG
610 620 630 640 650 660
DIVLCGFEYG RVRAMRDELG REVLEAGPSI PVEILGLSGV PAAGDEVTVV RDEKKAREVA
670 680 690 700 710 720
LYRQGKFREV KLARQQKSKL ENMFANMTEG EVHEVNIVLK ADVQGSVEAI SDSLLKLSTD
730 740 750 760 770 780
EVKVKIIGSG VGGITETDAT LAAASNAILV GFNVRADASA RKVIEAESLD LRYYSVIYNL
790 800 810 820 830 840
IDEVKAAMSG MLSPELKQQI IGLAEVRDVF KSPKFGAIAG CMVTEGTIKR HNPIRVLRDN
850 860 870 880 890
VVIYEGELES LRRFKDDVNE VRNGMECGIG VKNYNDVRVG DMIEVFEIIE IQRSID