B5XPE3

PR
Gene name
hisA
Protein name
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Names
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Species
Klebsiella pneumoniae (strain 342)
KEGG Pathway
kpe:KPK_1685
EC number
5.3.1.16: Interconverting aldoses and ketoses
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-70 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B5XPE3

Entry ID Method Resolution Chain Position Source
AF-B5XPE3-F1 Predicted AlphaFoldDB

No variants for B5XPE3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B5XPE3

No associated diseases with B5XPE3

No regional properties for B5XPE3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for B5XPE3

Functions

Description
EC Number 5.3.1.16 Interconverting aldoses and ketoses
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.

1 GO annotations of biological process

Name Definition
histidine biosynthetic process The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIIPALDLID GTVVRLHQGD YGQQRDYGSD PLPRLQSYAA QGAEVLHLVD LTGAKDPAKR
70 80 90 100 110 120
QIPLLKSLVA GVDVPVQVGG GVRTEADVAA LLEAGVARVV VGSTAVKSPE EVKGWFKRFG
130 140 150 160 170 180
PERLVLALDV RIDADGNKQV AVSGWQENSG VTLEELVESY LPVGLQHVLC TDISRDGTLA
190 200 210 220 230 240
GSNVSLYEEV CARYPQVAFQ SSGGIGDLKD IAALRGTGVR GVIVGRALLE GKFNVTEAIQ
CWQNG