B5X1G6

PR
Gene name
aktip (fts)
Protein name
AKT-interacting protein
Names
Fused toes protein homolog
Species
Salmo salar (Atlantic salmon)
KEGG Pathway
sasa:100194893
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-74 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B5X1G6

Entry ID Method Resolution Chain Position Source
AF-B5X1G6-F1 Predicted AlphaFoldDB

No variants for B5X1G6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B5X1G6

No associated diseases with B5X1G6

1 regional properties for B5X1G6

Type Name Position InterPro Accession
domain Ubiquitin-conjugating enzyme E2 79 - 227 IPR000608

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
FHF complex A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

6 GO annotations of biological process

Name Definition
apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
early endosome to late endosome transport The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
endosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
endosome to lysosome transport The directed movement of substances from endosomes to lysosomes.
lysosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNLNPFWSMS TNTGRKRSDG EEQSGEQQQQ QRASPARPSF GKKQLPSIPK NALPITKPAS
70 80 90 100 110 120
PAATAQLANG THASYGPFYL EYSLLAEFTL VIKQKLPGIY VQPSYKSALM WFGVIFIRHG
130 140 150 160 170 180
LYQDGVFKFT VYIPDNYPDG ECPRVVFDIP VFHPLVDPVS GELDVRRAFT KWRRNHNHIW
190 200 210 220 230 240
QVLMYARTVF YKINTMEPLN PEAAVLYDKD VQLFKSKVVD SVKLCNSHLF DQPKMDDPYA
250 260 270 280 290
ISFSSWNPAI HDDAKERMFT HKRRPEDHHK GLQVSGLSWV KPGSTQPFSK DDNPPQN