B5RCQ0

PR
Gene name
zipA
Protein name
Cell division protein ZipA
Names
Species
Salmonella gallinarum (strain 287/91 / NCTC 13346)
KEGG Pathway
seg:SG2460
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-210 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B5RCQ0

Entry ID Method Resolution Chain Position Source
AF-B5RCQ0-F1 Predicted AlphaFoldDB

No variants for B5RCQ0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B5RCQ0

1 associated diseases with B5RCQ0

[MIM: 616532]: Encephalopathy, acute, infection-induced, 7, herpes-specific (IIAE7)

A rare complication of human herpesvirus 1 (HHV-1) infection, occurring in only a small minority of HHV-1 infected individuals. It is characterized by hemorrhagic necrosis of parts of the temporal and frontal lobes. Onset is over several days and involves fever, headache, seizures, stupor, and often coma, frequently with a fatal outcome. {ECO:0000269|PubMed:26216125}. Note=Disease susceptibility is associated with variants affecting the gene represented in this entry.

Without disease ID
  • A rare complication of human herpesvirus 1 (HHV-1) infection, occurring in only a small minority of HHV-1 infected individuals. It is characterized by hemorrhagic necrosis of parts of the temporal and frontal lobes. Onset is over several days and involves fever, headache, seizures, stupor, and often coma, frequently with a fatal outcome. {ECO:0000269|PubMed:26216125}. Note=Disease susceptibility is associated with variants affecting the gene represented in this entry.

3 regional properties for B5RCQ0

Type Name Position InterPro Accession
domain Interferon regulatory factor, DNA-binding domain 1 - 112 IPR001346
domain Interferon regulatory factor-3 201 - 380 IPR019471
conserved_site Interferon regulatory factor, conserved site 26 - 58 IPR019817

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Single-pass type I membrane protein
  • Localizes to the Z ring in an FtsZ-dependent manner
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
cell septum assembly The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
FtsZ-dependent cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMQDLRLILI IVGAIAIIAL LVHGFWTSRK ERSSMFRDRP LKRMKSKRDD DSYDDDVEED
70 80 90 100 110 120
EGVGEVRVHR VNHAPGQSQE HDAPRQSPQH QYQPPYASAQ PRPAAPPQQQ APMQQPVQQP
130 140 150 160 170 180
VQPAPQPQQV QPSAPPVQPP QQQPAPPSQA PQPVAQPAPP PSAQTFQPAE PVVEAEPVVE
190 200 210 220 230 240
EAPVVEKPQR KEAVIIMNVA AHHGSELNGE VLLNSIQQSG FKFGDMNIFH RHLSPDGSGP
250 260 270 280 290 300
ALFSLANMVN PGTFDPEMTD FTTPGVTIFM QVPSYGDALQ NFKLMLQSAQ HIADEVGGVV
310 320
LDDQRRMMTP QKLREYQDRI REVMDANA