B5RAZ9

PR
Gene name
astD
Protein name
N-succinylglutamate 5-semialdehyde dehydrogenase
Names
Succinylglutamic semialdehyde dehydrogenase, SGSD
Species
Salmonella gallinarum (strain 287/91 / NCTC 13346)
KEGG Pathway
seg:SG1811
EC number
1.2.1.71: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B5RAZ9

Entry ID Method Resolution Chain Position Source
AF-B5RAZ9-F1 Predicted AlphaFoldDB

No variants for B5RAZ9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B5RAZ9

No associated diseases with B5RAZ9

3 regional properties for B5RAZ9

Type Name Position InterPro Accession
domain Aldehyde dehydrogenase domain 9 - 458 IPR015590
conserved_site Aldehyde dehydrogenase, cysteine active site 270 - 281 IPR016160
conserved_site Aldehyde dehydrogenase, glutamic acid active site 242 - 249 IPR029510

Functions

Description
EC Number 1.2.1.71 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
succinylglutamate-semialdehyde dehydrogenase activity Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H(2)O + NAD(+) = N-succinyl-L-glutamate + 2 H(+) + NADH.

2 GO annotations of biological process

Name Definition
arginine catabolic process to glutamate The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.
arginine catabolic process to succinate The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTLWINGDWI TGQGERRRKT NPVSAEILWQ GNDANAAQVA EACQVARAAF PRWARQPFAA
70 80 90 100 110 120
RQAIVEKFAA LLEAHKAELT EVIARETGKP RWEAATEVTA MINKIAISIK AYHARTGEQK
130 140 150 160 170 180
SELVDGAATL RHRPHGVLAV FGPYNFPGHL PNGHIVPALL AGNTLIFKPS ELTPWTGETV
190 200 210 220 230 240
IKLWERAGLP AGVLNLVQGG RETGQALSSL DDLDGLLFTG SASTGYQLHR QLSGQPEKIL
250 260 270 280 290 300
ALEMGGNNPL IIEDVANTDA AVHLTLQSAF ITAGQRCTCA RRLLVKQGAQ GDAFLARLVD
310 320 330 340 350 360
VAGRLQPGRW DDDPQPFIGG LISAQAAQHV MEAWRQREAL GGRTLLAPRK VKEGTSLLTP
370 380 390 400 410 420
GIIELTGVAD VPDEEVFGPL LNVWRYAHFD EAIRLANNTR FGLSCGLVST DRAQFEQLLL
430 440 450 460 470 480
EARAGIVNWN KPLTGAASTA PFGGIGASGN HRPSAWYAAD YCAWPMASLE SPELTLPATL
490
SPGLDFSLRE AV