Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B5GCP6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B5GCP6-F1 | Predicted | AlphaFoldDB |
No variants for B5GCP6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B5GCP6 | |||||
No associated diseases with B5GCP6
8 regional properties for B5GCP6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Protein kinase domain | 277 - 530 | IPR000719 |
| domain | SH2 domain | 156 - 255 | IPR000980 |
| domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | 278 - 526 | IPR001245 |
| domain | SH3 domain | 91 - 152 | IPR001452 |
| active_site | Tyrosine-protein kinase, active site | 392 - 404 | IPR008266 |
| binding_site | Protein kinase, ATP binding site | 283 - 305 | IPR017441 |
| domain | Tyrosine-protein kinase, catalytic domain | 277 - 526 | IPR020635 |
| domain | Tyrosine-protein kinase Yes, SH3 domain | 94 - 151 | IPR035751 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular amino acid catabolic process | The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASSAHSDSA | SSDAPAELPA | EILAAAPWSA | PADDSEHLRI | TAVRTFLTAP | QGCPYVIVRV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ETNQPGLYGL | GCASDPQRTL | AIRSVVDDYY | APMLLGRDPA | DIEDLHRLLF | NSGYWRGGSI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GQNALAGVDV | ALWDIKGKVA | GLPLHQLLGG | RAREAAEAYT | HVDGDNAGEI | AEKVLAAHER |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GYRHVRVQVS | VPGTDTYGTA | PRDAAEARRR | ELRAGSWDSL | AYLRHVPPVL | REIRERVGTG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VELLHDAHER | LTPSQARELV | HEVEDARLFF | LEDALAPEDA | AHFDQLRAAG | SVPLAVGELY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HDVMMYLPLL | QRQVIDFARI | RVPTLGGLTP | TRKLVAAVEL | FGARTAPHGP | GDVSPVGMAA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NLGLDLSSPA | FGVQEAATFR | EPTREVFPGT | PVPERGRFHG | SDRPGLGVDF | DEVAARKYPV |
| 430 | 440 | ||||
| PEPLRHDRWA | LLRNGDGSVQ | RP |