B5ED16

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Citrifermentans bemidjiense (strain ATCC BAA-1014 / DSM 16622 / JCM 12645 / Bem) (Geobacter bemidjiensis)
KEGG Pathway
gbm:Gbem_3641
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-52 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B5ED16

Entry ID Method Resolution Chain Position Source
AF-B5ED16-F1 Predicted AlphaFoldDB

No variants for B5ED16

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B5ED16

No associated diseases with B5ED16

3 regional properties for B5ED16

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 277 - 286 IPR020557
domain Fumarate lyase, N-terminal 8 - 301 IPR022761
domain Argininosuccinate lyase, C-terminal 365 - 434 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKDKLWGGR FTQPTDKFVE EFTASINFDK RLYHQDIRGS IAHATMLGKQ GIIPVADVES
70 80 90 100 110 120
IVSGLKTILE QIEAGEFDFS VSLEDIHMNI EARLSEKIGD AGKRLHTGRS RNDQVALDIR
130 140 150 160 170 180
LYLRDELVEV SAYIDLLIDA IIHQAEENLG VIMPGFTHLQ TAQPILFSHH MMAYHEMLKR
190 200 210 220 230 240
DKARMEDCLK RTNVLPLGAG ALAGTTFPID REYVAELLDF DGVTRNSLDS VSDRDFAMEF
250 260 270 280 290 300
CAASSILMVH LSRFSEELIL WSTSEFKFVE LSDSFCTGSS IMPQKKNPDV PELVRGKTGR
310 320 330 340 350 360
VNGNLVALLT LMKSLPLAYN KDMQEDKEPL FDTIDTVKGC LKVFADMVRE MKINPERMKT
370 380 390 400 410 420
AAAAGFSTAT DVADYLVRKG IPFRDAHEIV GKTVRYCIEN EMDIPELSLA EWQLFSGRIE
430 440 450
EDIFESITLQ ASVNARRATG GTALERVRAE IARAKEGR