Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B5BP49
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B5BP49-F1 | Predicted | AlphaFoldDB |
No variants for B5BP49
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B5BP49 | |||||
No associated diseases with B5BP49
1 regional properties for B5BP49
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major facilitator superfamily domain | 85 - 498 | IPR020846 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| intrinsic component of membrane | The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| ion transmembrane transport | A process in which an ion is transported across a membrane. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNNMSLKFPD | IAINSSESSD | DEDPSSKNEK | KDGSIKVVKG | LTDEKKVFEK | AKNDFDEALA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IIDDDDFEYT | KSEDDKVRRK | IDFFILPIMC | ITYGMQYLDK | TAVSYAAVYG | MKQEAHLSGY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VYSWLSTIFY | LGYMIAQYPA | GYLLQKFPIS | YFMFIAAFLW | SACVLLMAAC | SNRHGLLTLR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FFSGVFEGCV | NPAFVALTAM | WYKREEQPVR | VVSWYAFNGV | AIMVGALLGY | GTGHIKGSLQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NWKYPFLVIG | AISTAWSFVY | LFFPQNPVLA | RFLNAREKRI | AVERVRKNRT | GMETKKFKPS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QALEAFKDPQ | VILIVLYNGL | CQVTNAMSVF | SALIIQGIGY | SGINATLLTL | PSGAFAVAGM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IASGIFTHYF | KKGRIPLAMT | TSSLTIVGSI | MIWKIPHSNP | WPRVVGVWLF | CTISSGNAVI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LSLLSSNISG | YSKKVTVNAT | MFLFYSIGNI | VSPQLFKAGQ | TPEYIEGIQA | SLVSVCLFEG |
| 490 | 500 | 510 | 520 | ||
| VLALLAFYYI | FENARRDKLL | ENNPALGGEI | KNEEFLDKTD | REQIKFRYVW |