B4XYB8

PR
Gene name
aziB
Protein name
5-methyl-1-naphthoate synthase
Names
Azinomycin biosynthesis protein B
Species
Streptomyces sahachiroi
KEGG Pathway
ag:ABY83164
EC number
2.3.1.236: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1718-1779 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4XYB8

Entry ID Method Resolution Chain Position Source
AF-B4XYB8-F1 Predicted AlphaFoldDB

No variants for B4XYB8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4XYB8

No associated diseases with B4XYB8

1 regional properties for B4XYB8

Type Name Position InterPro Accession
domain Flavodoxin-like fold 1 - 200 IPR003680

Functions

Description
EC Number 2.3.1.236 Transferring groups other than amino-acyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
acyltransferase activity, transferring groups other than amino-acyl groups Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
phosphopantetheine binding Binding to phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate).

3 GO annotations of biological process

Name Definition
antibiotic biosynthetic process The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
organic cyclic compound biosynthetic process The chemical reactions and pathways resulting in the formation of organic cyclic compound.
polyketide biosynthetic process The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAENVQNPPV EPLAVIGMSC RFAPDLDTPG RLWEFLRAGG SAVGEMPDRR WDPYVTDSRT
70 80 90 100 110 120
RDILRTTTRK GSFMRDIEGF DAEFFQITPR EAEYIDPQQR IMLELAWEAL CDAGLPPTSL
130 140 150 160 170 180
AGTDASVYVA ANSNDYGRRL LEDLDRTGAW AVNGTTFYGI ANRISYFLDA HGPSMAVDTA
190 200 210 220 230 240
CAGSLTALHV AGQALHRGET SVAIVGGINI MASPALVVAL DAASATSPDG RSKSFDKAAD
250 260 270 280 290 300
GYGRGEGGGV VVLKRLSDAV RDGDPVHGLV LASGVFQDGR SDGMMAPNGS AQQRMLEEIY
310 320 330 340 350 360
RRSGIDPGTV QYVEAHGTGT QLGDAAEAQA IGNVFGPGRD GDNPLLIGTL KPNVGHVEAA
370 380 390 400 410 420
SGIAGVIKVL LGMRHGELPP SPHEEPDPGL GLEARGLRLV AEPTPWPRGE HGMRAGVSSY
430 440 450 460 470 480
GVGGSIAHAV LQQAPPRPDR TERPAAAATG RPQVFPLSAA SEQGVRGLAG SVAAWLRAHP
490 500 510 520 530 540
ETALDDLAHT FTARRSHLSR RAAVVAGTTE ELLGGLDALA GGEKSPAVAL ASASGFGDGG
550 560 570 580 590 600
AAGPAWVFSG HGAQWSGMGR ELLTTEPVFA QVIDELAPVF SEELGWTPRE AIEAGGPWTV
610 620 630 640 650 660
VRTQAMTFAM QVALAEVWSD LGLRPGAIIG HSVGEIAAAA VAGSLDRAEA ARFACRRARA
670 680 690 700 710 720
LGKIAGRGAM AMVPMAFADV EQRVAGRDAV VAAIAASPLS TVVSGDTAAV EALLADLEAD
730 740 750 760 770 780
GIQARRVNTD VAFHSPHVQE ILDEVRQAAA ALRAGTPRVT LYSTALADPR SDAPREGEYW
790 800 810 820 830 840
ATNLADPVRF HQAVRAALDD GTRVFLEVSS HPVVAHSITE TALDAGVPDA HVAITLRREQ
850 860 870 880 890 900
PEQRTVLANL ARLHSLGTPV TWSYDGDLVD VPAVRWQHKP YWIFPDTAPE QGAGLGHDPQ
910 920 930 940 950 960
THTLIGARTT VASAPVQRVW QTELHMENRP YAQSHKVVGV ETVPASVVLN SFITAATNEG
970 980 990 1000 1010 1020
ERACGLRDIV FRIPLAAHPT RVVQVVLEQD KVRIASRIKR DQESGGVRDD EWLTHTTATV
1030 1040 1050 1060 1070 1080
VHEPEVGARP MEDPDVIRAR CPVSWTWAKV DGIFRTMGVD GYTFPWVVEE LLRGEDEQFS
1090 1100 1110 1120 1130 1140
TITVDHTPKL HPSSWTAVVD AALTASGVLV MDENSNVLRT CSHLESLSFV GPPPPRIHVH
1150 1160 1170 1180 1190 1200
TVRDPRTPDT ISMTVADESG AVVCEARGLR YVKVQDIGSG AVGPRDLVHE LAWEPVEVPA
1210 1220 1230 1240 1250 1260
DAPVPSQALV VGGAAGGPAL VEALTARGVR ARAVPDATAI GDASLTCADV VVVAPEALLP
1270 1280 1290 1300 1310 1320
GEAPEQAARR CAQLLVDAVQ QVAAVPDERR RPRVWALTRE VRAGATEAAL AHAPLWGAGR
1330 1340 1350 1360 1370 1380
IVAGERPDLW GGVIDVAENA VPQQVASLIG ALPHTEDVLS LDSEGVTAAR LRQVARPAER
1390 1400 1410 1420 1430 1440
EPVDCRPDGT YLVTGGLGAL GLEAARHLVE QGARRLVLIG RRGLPSRSRW DQVDDPAVAA
1450 1460 1470 1480 1490 1500
QIAEVVALEA AGATVRVLSL DISDAEATAR ALDPGALDMP PVRGIVHCAG VVSDALVEKT
1510 1520 1530 1540 1550 1560
GAANLDTTMG PKADGAMVLH RLFPAGTLDF FTMFSSCGQL ARLTGQVSYA SANSFLDALA
1570 1580 1590 1600 1610 1620
ALRRSRGETG TTSFAWAQWI GRGMGETTGR ATILEAESRG LGGITVSEAL RSWAYADRFA
1630 1640 1650 1660 1670 1680
LPYAAVMRVM PDHTLPVFSH LSVTDAGAQS ADAGGVDWAT VPAGELPELV LKVTHEQVAA
1690 1700 1710 1720 1730 1740
ELNLAVDDIA IDQPLLELGV DSVLTVALRV RLHRCFAVDL PPTILWSNPT VRALAEFLAA
1750 1760 1770
EVGGATADAE ETDPVAGLPA PQQGSGTAEQ LDAVAAAAG