B4U965

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Hydrogenobaculum sp (strain Y04AAS1)
KEGG Pathway
hya:HY04AAS1_0990
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

850-944 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4U965

Entry ID Method Resolution Chain Position Source
AF-B4U965-F1 Predicted AlphaFoldDB

No variants for B4U965

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4U965

No associated diseases with B4U965

8 regional properties for B4U965

Type Name Position InterPro Accession
domain Helicase, C-terminal 464 - 680 IPR001650
domain SecA DEAD-like, N-terminal 6 - 444 IPR011115
domain SecA Wing/Scaffold 671 - 877 IPR011116
domain SecA, preprotein cross-linking domain 288 - 400 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 98 - 306 IPR014001
domain SecA motor DEAD 3 - 673 IPR014018
conserved_site SecA conserved site 542 - 557 IPR020937
domain SecA, C-terminal helicase domain 462 - 643 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIGYVLKKIL GTKNDREIKK IRKWVEKINA LEESLDKLSN KDIVLKAQDL YFRVNQNEHI
70 80 90 100 110 120
KQAIIEGEMV EELIEAFALV REASKRTMGL RQFDVQLIGG IVLYQGKIAE MKTGEGKTLV
130 140 150 160 170 180
AAAPAFFTAL TDTGVHVVTV NDYLAKRDAT WIGPIYRFLG LDVGVINSDN MSYIIDWQDP
190 200 210 220 230 240
EKAMEAIEKD IRVWPKGMVG DAIDYSKIDV HAKTSYFTKA ISVERAKAYE AHITYGTNNE
250 260 270 280 290 300
FGFDYLRDNL AVSKDQIVQV KGHGYAIVDE IDSILIDEAR TPLIIAGPSN LDNKVVLQAN
310 320 330 340 350 360
EFVQTLEIEK DFIVDEKNRT AMLTEEGIEK AEKYFNIQNL YDIRHIDLVH AINKALLAHN
370 380 390 400 410 420
LYKKDVHYMV KDGEILIVDE FTGRALPGRR WSEGLHQAIE AKEGVEIQEE NQTLATTAFQ
430 440 450 460 470 480
NYFKLYKKLA GMTGTAETEA LEFKEIYSLD VVVIPTNKPN IRKDLPDAIF KTKKEKWEYI
490 500 510 520 530 540
AKVIEENHAK GRPILVGTVS IEDSETLSKL LEQRGIKHNV LNAKQHEKEA WIIAQAGRKG
550 560 570 580 590 600
AVTIATNMAG RGTDILLGGN PEFLAREILK QKGIDEDKAT EEEWKQAYEE ATKITQKEKE
610 620 630 640 650 660
EVIKAGGLLV IGTERHESRR VDNQLRGRAG RQGDPGESRF ILSLEDDLLR IFGGDRVKKL
670 680 690 700 710 720
MEFMKIPEGE PIESSIVSKS LEGAQERVEL QNFQSRKRLL EYDEVINIQR SVVYDIRRSI
730 740 750 760 770 780
LFQDDIKEEI KDFIKDVIHT QVFTLLTEDE PELWELEPLK TFFKEWIDLD LPEKFEAKDR
790 800 810 820 830 840
EELEEEIFKL VMEKYAQKEQ EIGEKTMREI EKVFTLNIID NLWREQLHTI DKLREGIYLR
850 860 870 880 890 900
SYAQRDPLVE FKKEAFRLFE ELMLNFKISA IQSIMNAQIS KEELEQQEQN MFNLEIDTLN
910 920 930 940
KSMAISEALE NIAKEFQEKR PRFRTLKDRL EERKKKLEKK GESA