B4TNU5
Gene name |
wecF |
Protein name |
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase |
Names |
4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase |
Species |
Salmonella schwarzengrund (strain CVM19633) |
KEGG Pathway |
sew:SeSA_A4138 |
EC number |
2.4.1.325: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B4TNU5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B4TNU5-F1 | Predicted | AlphaFoldDB |
No variants for B4TNU5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B4TNU5 | |||||
No associated diseases with B4TNU5
No regional properties for B4TNU5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for B4TNU5 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.325 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 4-acetamido-4,6-dideoxy-D-galactose transferase activity | Catalysis of the reaction: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol <=> H+ + alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP. |
| fucosyltransferase activity | Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| enterobacterial common antigen biosynthetic process | The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria. |
| fucosylation | The covalent attachment of a fucosyl group to an acceptor molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTVLIHVLGS | DIPHHNHTVL | RFFNDTLAAT | SEHAREFMVA | GEDNGFTESC | PALSLRFYGS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KKALAQAVIA | KAKANRRQRF | FFHGQFNTSL | WLALLSGGIK | PAQFYWHIWG | ADLYEVSHGL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KFRLFYPLRR | IAQGRVGGVF | ATRGDLSYFA | RQHPGVRGEL | LYFPTRMDPS | LNSMAKERQR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AGKLTILVGN | SGDRSNEHIT | ALRAVYQQFG | DTVNVVVPMG | YPANNQAYID | EVRQVGLALF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SAENLQILSE | KMEFDAYLAL | LRQCDLGYFI | FARQQGIGTL | CLLIQADIPC | VLNRDNPFWQ |
| 310 | 320 | 330 | 340 | 350 | |
| DMAEQHLPVL | FTTDDLNEQV | VREAQRQLAS | VDKSGITFFS | PNYLQPWHNA | LRIAAGEAE |