B4TJ06

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Salmonella heidelberg (strain SL476)
KEGG Pathway
seh:SeHA_C3581
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

72-326 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4TJ06

Entry ID Method Resolution Chain Position Source
AF-B4TJ06-F1 Predicted AlphaFoldDB

No variants for B4TJ06

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4TJ06

No associated diseases with B4TJ06

7 regional properties for B4TJ06

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 391 - 560 IPR000795
domain Small GTP-binding protein domain 395 - 550 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 52 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 316 - 366 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 57 - 95 IPR013575
domain Translation initiation factor IF- 2, domain 3 667 - 781 IPR023115
domain Translation initiation factor IF-2, domain II 567 - 660 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDVTLKALA AERQVSVDRL VQQFADAGIR KSADDSVSAQ EKQTLLAHLN REAVSGPDKL
70 80 90 100 110 120
TLQRKTRSTL NIPGTGGKSK SVQIEVRKKR TFVKRDPQEA ERLAAEEQAQ REAEEQARRE
130 140 150 160 170 180
AEEQAKREAQ QKAEREAAEQ AKREAAEKAK REAAEKDKVS NQQTDDMTKT AQAEKARREN
190 200 210 220 230 240
EAAELKRKAE EEARRKLEEE ARRVAEEARR MAEENKWTAT PEPVEDTSDY HVTTSQHARQ
250 260 270 280 290 300
AEDENDREVE GGRGRGRNAK AARPAKKGKH AESKADREEA RAAVRGGKGG KRKGSSLQQG
310 320 330 340 350 360
FQKPAQAVNR DVVIGETITV GELANKMAVK GSQVIKAMMK LGAMATINQV IDQETAQLVA
370 380 390 400 410 420
EEMGHKVILR RENELEEAVM SDRDTGAAAE PRAPVVTIMG HVDHGKTSLL DYIRSTKVAS
430 440 450 460 470 480
GEAGGITQHI GAYHVETDNG MITFLDTPGH AAFTSMRARG AQATDIVVLV VAADDGVMPQ
490 500 510 520 530 540
TIEAIQHAKA AGVPVVVAVN KIDKPEADPD RVKNELSQYG ILPEEWGGES QFVHVSAKAG
550 560 570 580 590 600
TGIDELLDAI LLQAEVLELK AVRKGMASGA VIESFLDKGR GPVATVLVRE GTLHKGDIVL
610 620 630 640 650 660
CGFEYGRVRA MRNELGQEVL EAGPSIPVEI LGLSGVPAAG DEVTVVRDEK KAREVALYRQ
670 680 690 700 710 720
GKFREVKLAR QQKSKLENMF ANMTEGEVHE VNIVLKADVQ GSVEAISDSL LKLSTDEVKV
730 740 750 760 770 780
KIIGSGVGGI TETDATLAAA SNAILVGFNV RADASARKVI ESESLDLRYY SVIYNLIDEV
790 800 810 820 830 840
KAAMSGMLSP ELKQQIIGLA EVRDVFKSPK FGAIAGCMVT EGTIKRHNPI RVLRDNVVIY
850 860 870 880 890
EGELESLRRF KDDVNEVRNG MECGIGVKNY NDVRVGDMIE VFEIIEIQRT IA