B4SV14

PR
Gene name
accA
Protein name
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Names
ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha
Species
Salmonella newport (strain SL254)
KEGG Pathway
see:SNSL254_A0254
EC number
2.1.3.15: Carboxy- and carbamoyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-91 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4SV14

Entry ID Method Resolution Chain Position Source
AF-B4SV14-F1 Predicted AlphaFoldDB

No variants for B4SV14

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4SV14

No associated diseases with B4SV14

1 regional properties for B4SV14

Type Name Position InterPro Accession
domain Acetyl-coenzyme A carboxyltransferase, C-terminal 35 - 296 IPR011763

Functions

Description
EC Number 2.1.3.15 Carboxy- and carbamoyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
acetyl-CoA carboxylase complex A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.

3 GO annotations of molecular function

Name Definition
acetyl-CoA carboxylase activity Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
carboxyl- or carbamoyltransferase activity Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).

2 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
malonyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSLNFLDFEQ PIAELEAKID SLTAVSRQDE KLDINIDEEV HRLREKSVEL TRKIFADLGA
70 80 90 100 110 120
WQVAQLARHP QRPYTLDYVR LAFDEFDELA GDRAYADDKA IVGGIARLEG RPVMIIGHQK
130 140 150 160 170 180
GRETKEKIRR NFGMPAPEGY RKALRLMEMA ERFNMPIITF IDTPGAYPGV GAEERGQSEA
190 200 210 220 230 240
IARNLREMSR LNVPVICTVI GEGGSGGALA IGVGDKVNML QYSTYSVISP EGCASILWKS
250 260 270 280 290 300
ADKAPLAAEA MGIIAPRLKE LKLIDSIIPE PLGGAHRNPE AMAASLKAQL LEDLADLDVL
310
STDDLKNRRY QRLMSYGYA