B4SCE7

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1)
KEGG Pathway
pph:Ppha_0398
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

67-418 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4SCE7

Entry ID Method Resolution Chain Position Source
AF-B4SCE7-F1 Predicted AlphaFoldDB

No variants for B4SCE7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4SCE7

No associated diseases with B4SCE7

5 regional properties for B4SCE7

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 483 - 653 IPR000795
domain Small GTP-binding protein domain 485 - 643 IPR005225
domain Translation initiation factor IF-2, N-terminal 411 - 459 IPR006847
domain Translation initiation factor IF- 2, domain 3 763 - 876 IPR023115
domain Translation initiation factor IF-2, domain II 661 - 755 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MALEDMEKKY RISDIARELQ VSPQEVLLFV KQEGGRVAST SSMVGEEIHG LIFGHFSVEK
70 80 90 100 110 120
KMVDETKKIR AEKEKRLSRL EEQSRKTYEK EQHLSETLSP PAPPLVVVHE PKKEVIVAAP
130 140 150 160 170 180
IENIPEPPSK PLEIPVAETP ASEEPDAPPA VTELIEQPVV IEQQPLAPVS DAPVPPVIIE
190 200 210 220 230 240
LPVPSEVPES QVLPESRVLP ESQVLSESPL LPEPPVLSEP QEQQELPELP ELPEIPALPE
250 260 270 280 290 300
PAPKKEEPSV NEHLVSFDAP QMMGGLTVLG TLDMQAGRHK KNRKKNFQEQ ADALKDEFEP
310 320 330 340 350 360
KPAEESRVEE KVVVAKKPPV KAAADVKPKP VVADSSSSAK KKGKKKKKPA VDDKVISANI
370 380 390 400 410 420
QKTISGIDDR SSTGSRQKFR KMRRNERERE HEEDEAFREA QRLVVRVTEY ASPHELAELM
430 440 450 460 470 480
GITAKDIIQK CFALGKFVTI NQRLDKESIE LIALEFGFEA EFISEVEATA VIVTEDAEAD
490 500 510 520 530 540
MQTRPPVVTI MGHVDHGKTS LLDYIRNSKV VAGESGGITQ HIGAYEVTVE GDRKITFLDT
550 560 570 580 590 600
PGHEAFTAMR ARGAQVTDIV ILVVAADDSV MPQTIEAINH AKAAGVPIVV ALNKIDKVEA
610 620 630 640 650 660
NPEKIKTQLS EAGVLVEEWG GVYQCQEISA KKGIGIAELM EKVLTEAEMR ELRGNYSREV
670 680 690 700 710 720
PASGIIVESE LDKGKGVIST VLVQRGILKV GDPFVAGNTM GKVRALMDER GKRIPFANPS
730 740 750 760 770 780
QPVRVLGFED LPQSGDALTV MVTDREARDL AQKRQVIRRE HDFRRSTRVK LDSIARQIKE
790 800 810 820 830 840
GLMKELSVII KADTDGSIQA LADGLMKIQN EEVKVQIIHQ GVGQITETDV LLAAASDAII
850 860 870 880 890 900
IGFRVRPNVN AKKLAEKEDL DVRFYSVIYH VLEDVEKALE GMLSPELHEE SLGSLEIRQI
910 920 930 940 950 960
FKVPKIGNVG GCYMLEGKMF RDSKVRLLRD GVQIYEGQLA ALKRFKDDVK EVDAGYECGM
970 980
SLKNYDDIKV GDIVEAYKIV EKKRKL