B4SC75

PR
Gene name
purA
Protein name
Adenylosuccinate synthetase
Names
AMPSase, AdSS, IMP--aspartate ligase
Species
Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1)
KEGG Pathway
pph:Ppha_0322
EC number
6.3.4.4: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

97-167 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4SC75

Entry ID Method Resolution Chain Position Source
AF-B4SC75-F1 Predicted AlphaFoldDB

No variants for B4SC75

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4SC75

No associated diseases with B4SC75

2 regional properties for B4SC75

Type Name Position InterPro Accession
binding_site Adenylosuccinate synthase, GTP-binding site 20 - 27 IPR018220
active_site Adenylosuccinate synthase, active site 142 - 153 IPR033128

Functions

Description
EC Number 6.3.4.4 Other carbon--nitrogen ligases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
adenylosuccinate synthase activity Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.
GTP binding Binding to GTP, guanosine triphosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.

1 GO annotations of biological process

Name Definition
'de novo' AMP biosynthetic process The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MESKKFRTPS QSATVIVGTQ FGDEGKGKLV DYLSDKYDIV VRYQGGANAG HTICFDNKTV
70 80 90 100 110 120
VLHLIPSGIF HKGCVCVIGN GVVIDPAALL DEIRKVEELG YEVTGRLFIS HNAHLIMPYH
130 140 150 160 170 180
KLLDSLHESA QGDQKIGTTG RGIGPSYEDK FARKGIRVVD LLNPEVLKEK LRENLAAKNK
190 200 210 220 230 240
LFKNIYEKEE IDVETMVREY EDFDKIIDPY VTNTQLYLNR QLQEGKTVLL EGAQGCLLDV
250 260 270 280 290 300
DHGTYPYVTS SNPTSGGAST GSGIAPNYIG KVIGVCKAYM TRVGNGAFPT ELLDETGERL
310 320 330 340 350 360
GKIGHEFGAT TGRKRRCGWI DLVALRYSLT INGVTEIALT KLDVLDTFEE IRICTSYMLD
370 380 390 400 410 420
GKEIHDFPTD HQTLSRVTPL YTTLKGWMAS NAHARSFSEM QPEAQNYVTF LEDELQVQVT
430
FISVGPGREE TVFR