Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for B4S4S6

Entry ID Method Resolution Chain Position Source
AF-B4S4S6-F1 Predicted AlphaFoldDB

No variants for B4S4S6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4S4S6

No associated diseases with B4S4S6

5 regional properties for B4S4S6

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 433 - 603 IPR000795
domain Small GTP-binding protein domain 436 - 593 IPR005225
domain Translation initiation factor IF-2, N-terminal 359 - 409 IPR006847
domain Translation initiation factor IF- 2, domain 3 712 - 826 IPR023115
domain Translation initiation factor IF-2, domain II 613 - 705 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSLEEKEMKY RISDIARELQ VSPQEVLHFV KQEGAKVAST SSMVKSDMRE LILGHFSDEK
70 80 90 100 110 120
RLVDQTRKIR EEKRQRLTRL EEQSRKTYEK EQQLKDSIAV FPEPGPVLKK DHVHEEPEKP
130 140 150 160 170 180
AIVISESEPE VEPEVEPEQP AAAQEAEEAV PTEAVSVPEP VEQERVVPAP EKPEAEKPVP
190 200 210 220 230 240
EQSSTMKAQA SPEMQVTYEK PKNIGGLTVL GSIDVRSALD RGSESDRKKK NRKKRFKEQA
250 260 270 280 290 300
DELKGEFENA GKAEGDKKPA KSGEAKTKAP KKAAGTTGSA AEDTTSSKKK KGGKKKKPAV
310 320 330 340 350 360
DEKVISQNIR STISGMDDSS GGSGSRQKFR KMRKIEREKE LEAAEAVKEA ERSIVRVTEF
370 380 390 400 410 420
ATAHELADLM GITAKEIIQR CFTLGKFVTI NQRLDKETIE LVALEFGFEA EFVSEVEATE
430 440 450 460 470 480
VFEVHDDSED LEIRPPVVTI MGHVDHGKTS LLDYIRSSNV VAGESGGITQ HIGAYEVTLD
490 500 510 520 530 540
NGRSITFLDT PGHEAFTAMR ARGAQVTDIV ILVVAADDSV MPQTIEAINH SKAANVPIVV
550 560 570 580 590 600
AINKIDKPEA NPEKIRAQLS EAGVLVEDWG GEYQCQEISA KQGMGMHELM EKVLMEAEIR
610 620 630 640 650 660
ELKANFSREA NSRGIIVESE LDKGKGVIST VLVQRGFLKV GDPFVAGNTM GRVRALMDER
670 680 690 700 710 720
GRRIKEAGPS QPVRVLGFED LPQSGDEFVV MPTDKEAREI AQKRQIIRRE HEFRRSTRVK
730 740 750 760 770 780
LDSIARQIKE GLMKELSVII KADTDGSIQA LADGLMKIHN EEVKVQIIHQ GVGQITETDV
790 800 810 820 830 840
LLAAASDAII IGFRVRPNVN AKRLAEKEDL DVRFYSVIYH VIEEIEQALE GMLSPELHEE
850 860 870 880 890 900
SLGSLEIRQV FRVPKIGNVG GCYMLEGKIF RDSKVRLLRE GVQIYDGVLD SLKRFKDDVK
910 920 930
EVDAGYECGL NLKGYGDIKV GDIVEAYRIV EKKRKL