B4RXT8

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)
KEGG Pathway
amc:MADE_1008920
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

10-310 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4RXT8

Entry ID Method Resolution Chain Position Source
AF-B4RXT8-F1 Predicted AlphaFoldDB

No variants for B4RXT8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4RXT8

No associated diseases with B4RXT8

7 regional properties for B4RXT8

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 368 - 537 IPR000795
domain Small GTP-binding protein domain 371 - 526 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 50 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 294 - 344 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 59 - 93 IPR013575
domain Translation initiation factor IF- 2, domain 3 644 - 758 IPR023115
domain Translation initiation factor IF-2, domain II 543 - 638 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADVSIEKLA SDIGTTVDRL VGQFKDAGIS KSAGEQVNED EKQKLLDHLS KQHGSAAEPT
70 80 90 100 110 120
RMTLKRKTTS TLSVGKSKEV KVEVRKKRTY VKRSDIEEQQ RQAEEEAKRL EEEARLKREA
130 140 150 160 170 180
EEKAAAEAKK AAEEKARKAQ EAKKAAEEER VRRAEQAKKE AEARKKDEPE LTEAEKAEAE
190 200 210 220 230 240
AARQEEERLR KAQEEEAQKK LEEDAKKAAD EARKLAEENE RRWKEEEERR KKAEAEEVHL
250 260 270 280 290 300
HSNRYAQEAE DEEDMQVERS SRRRRKSKKN AGEHLKQGFN KPAAPVERVV KLGATITVGE
310 320 330 340 350 360
LASKLAIKSN EVIKTMMKMG EMATINQVLD QDTAVLVIEE MGHKYELVND NALEDELLAD
370 380 390 400 410 420
GTDGEKTSRA PVVTIMGHVD HGKTSLLDYI RRAKVADGEA GGITQHIGAY KVQTDNGEIT
430 440 450 460 470 480
FLDTPGHAAF TAMRARGATA TDIVILVVAA DDGVMPQTKE AVQHARAAGV PLIVAVNKMD
490 500 510 520 530 540
KETADPDRVK TELSQLEVIS EEWGGEHQFC NVSAKTGMGV DELLEAIVLQ SELLDLQAVA
550 560 570 580 590 600
EGPGRGIVIE SRLDKGRGPV ASVLVQEGQL RAGDILLCGE EYGRVRAMRD ENGKDMKLAG
610 620 630 640 650 660
PSTPVEVLGL SGVPVAGEDA AVVKDERKAR EVAAKRHQKK RELKLARQQK AKLENMFANM
670 680 690 700 710 720
ESGDVSELNI VLKADVQGSV EAISESLIKL STSEVKVNIV GSGVGGITET DATLAAASGA
730 740 750 760 770 780
IVLGFNVRAD ATARRVLEAE EIDLRYYSVI YNLIDEVKAA MSGMLAPEFK QEIIGLAEVR
790 800 810 820 830 840
DVFKSPKLGA IAGCMVTEGN VKRSNPIRVL RDNVVIYEGE LESLRRFKDD VQDVRNGMEC
850 860
GIGVKNYNDV KVGDQIEVFE IVEVKREI