Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B4QT24
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B4QT24-F1 | Predicted | AlphaFoldDB |
21 variants for B4QT24
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| 112 | Q>L | strain: North Carolina 29 [UniProt] | No | ||
| 142 | R>Q | strain: North Carolina 19, Zimbabwe 4 and Zimbabwe 70 [UniProt] | No | ||
| 145 | K>R | strain: Zimbabwe 4 and Zimbabwe 70 [UniProt] | No | ||
| 146 | T>N | strain: Colombia 32 [UniProt] | No | ||
| 156 | P>S | strain: North Carolina 19, Mexico 12 and Zimbabwe 4 [UniProt] | No | ||
| 171 | N>Q | strain: Zimbabwe 70 and Zimbabwe 79 [UniProt] | No | ||
| 172 | E>A | strain: Zimbabwe 70 and Zimbabwe 79 [UniProt] | No | ||
| 173 | V>D | strain: Mexico 2, Mexico 12, Mexico 23, Mexico 31, North Carolina 19, North Carolina 29, Zimbabwe 4, Zimbabwe 19, Zimbabwe 21, Zimbabwe 50, Zimbabwe 70, Zimbabwe 79 [UniProt] | No | ||
| 182 | V>del | strain: Colombia 32, Mexico 2, Mexico 23, Mexico 31, Zimbabwe 19, Zimbabwe 21, Zimbabwe 50 [UniProt] | No | ||
| 185 | V>I | strain: Colombia 32 [UniProt] | No | ||
| 185 | V>M | strain: Mexico 2, Mexico 23, Mexico 31, Zimbabwe 19, Zimbabwe 21, Zimbabwe 50 [UniProt] | No | ||
| 192 | M>I | strain: Zimbabwe 4 [UniProt] | No | ||
| 192 | M>V | strain: Mexico 2, Mexico 23, Mexico 31, Zimbabwe 19, Zimbabwe 21 and Zimbabwe 50 [UniProt] | No | ||
| 193 | A>S | strain: Zimbabwe 4 [UniProt] | No | ||
| 212 | H>Q | strain: Colombia 32, Mexico 12, North Carolina 19, Zimbabwe 4 and Zimbabwe 70 [UniProt] | No | ||
| 220 | E>V | strain: Mexico 2, Mexico 23, Mexico 31, Zimbabwe 19, Zimbabwe 21 and Zimbabwe 50 [UniProt] | No | ||
| 228 | A>V | strain: Mexico 12 [UniProt] | No | ||
| 238 | P>Q | strain: Mexico 2, Mexico 12, Mexico 23, Mexico 31, North Carolina 19, Zimbabwe 19, Zimbabwe 21, Zimbabwe 50 [UniProt] | No | ||
| 245 | R>P | strain: Mexico 12 [UniProt] | No | ||
| 265 | M>I | strain: Mexico 2, Mexico 12, Mexico 23, Mexico 31, Zimbabwe 4, Zimbabwe 19, Zimbabwe 21, Zimbabwe 50, Zimbabwe 70, Zimbabwe 79 [UniProt] | No | ||
| 274 | L>I | strain: Mexico 12 [UniProt] | No |
No associated diseases with B4QT24
No regional properties for B4QT24
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for B4QT24 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromosome, centromeric region | The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| telomere cap complex | A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| telomeric DNA binding | Binding to a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| telomere capping | A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGTQMSAFL | RQYLADEDKK | IRAQFKESDP | NNKLILWMHE | KTRITEEDLA | RPYTEDEVKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LCLRTKVKVD | MTAWNCLWEA | KKRFEAKGRF | VNKSERFINR | MYMKAVRKKM | VQPYPEEFVA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QRREVVAAET | KKHNISRLDR | WRRKKTQNLS | AQESSPARGA | HASFIDAMQT | NEVQVNANLS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SVSQVNFQVE | AMARPAVSSS | DLSGIGDDED | EHQQSEFQDE | HINCPETAIN | ENSVRCDPIN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SGRMRTGCIN | SQGNNNTESD | PDYYMFGTQL | SSLLRPTSTQ | EPDDQVNCPE | TEMNESWVRC |
| 310 | 320 | 330 | |||
| DQINSESMSI | GPSIDSEGTI | TFQNSESEPI | DVDSIA |