B4NSS9

PR
Gene name
GD17699
Protein name
Serine/threonine-protein kinase GD17699
Names
Doublecortin-like and CAM kinase-like protein
Species
Drosophila simulans (Fruit fly)
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

379-483 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4NSS9

Entry ID Method Resolution Chain Position Source
AF-B4NSS9-F1 Predicted AlphaFoldDB

No variants for B4NSS9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4NSS9

No associated diseases with B4NSS9

5 regional properties for B4NSS9

Type Name Position InterPro Accession
domain Protein kinase domain 473 - 731 IPR000719
domain Doublecortin domain 149 - 240 IPR003533-1
domain Doublecortin domain 304 - 392 IPR003533-2
active_site Serine/threonine-protein kinase, active site 590 - 602 IPR008271
binding_site Protein kinase, ATP binding site 479 - 502 IPR017441

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

2 GO annotations of biological process

Name Definition
intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MELEKVKINS LHCNDAVLSS LQASPSATHP QSVPSKANAV TEASIIEKTN LQHNVQEDNS
70 80 90 100 110 120
YNRDCDSPVS SSSEPEKELD DLRYLHSSSL TNSVVVGKST GSLNGAYSIT SVTSKTKTLE
130 140 150 160 170 180
PNSASGSACL TIAPTADHIK KRIPSSRTPT RKALRIKFYR NGDRFYPGIT IPVSNERYRS
190 200 210 220 230 240
FERLFEDLTR LLEENVKIPG AVRTIYNMCG KKITSLDELE DGQSYVCSCN NENFKKVEYN
250 260 270 280 290 300
TGSQPLSNLT LTSSRSNSHR LDKCRPSSPL KNGLLAGSSP LPTCGGGTGN GSPHIASRSS
310 320 330 340 350 360
DRVTVVHPRI VTLIRSGTKP RRIMRLLLNK RNSPSFDHVL TAITQVVRLD TGYVRKVFTL
370 380 390 400 410 420
SGVSVVRLSD FFGSDDVFFA YGTERINTAE DFKLEAEEHR AINVIRKTMR TTGTTCKGPK
430 440 450 460 470 480
PKMPIKSKKV YPPVVDSEAF KAATTPEDDS HAALLTSTGM EINELPSNIR NTYTLGRIIG
490 500 510 520 530 540
DGNFAIVFKI KHRQTGHSYA LKIIDKNKCK GKEHYIDAEV RVMKKLNHPH IISLILSVDQ
550 560 570 580 590 600
NTNMYLVLEY VSGGDLFDAI TQVTRFSESQ SRIMIRHLGA AMTYLHSMGI VHRDIKPENL
610 620 630 640 650 660
LVKLDEHGHV LELKLADFGL ACEVNDLLYA VCGTPTYVAP EILLEVGYGL KIDVWAAGII
670 680 690 700 710 720
LYILLCGFPP FVAPDNQQEP LFDAIISGIY EFPDPYWSDI GDGVRDLIAN MLQADPDVRF
730 740
TSEDILDHPW TIGNQNECTT YKR