B4NE96

PR
Gene name
Pgam5
Protein name
Serine/threonine-protein phosphatase Pgam5, mitochondrial
Names
Phosphoglycerate mutase family member 5 homolog
Species
Drosophila willistoni (Fruit fly)
KEGG Pathway
dwi:6648756
EC number
3.1.3.16: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

36-106 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4NE96

Entry ID Method Resolution Chain Position Source
AF-B4NE96-F1 Predicted AlphaFoldDB

No variants for B4NE96

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4NE96

No associated diseases with B4NE96

No regional properties for B4NE96

Type Name Position InterPro Accession
No domain, repeats, and functional sites for B4NE96

Functions

Description
EC Number 3.1.3.16 Phosphoric monoester hydrolases
Subcellular Localization
  • Mitochondrion outer membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.

2 GO annotations of molecular function

Name Definition
myosin phosphatase activity Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.
phosphoprotein phosphatase activity Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity.

1 GO annotations of biological process

Name Definition
protein dephosphorylation The process of removing one or more phosphoric residues from a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRKFTAFACG TGAGLAAFYL QRLRDPKQTA WVHNSWTNSE RPVDSWALWD SNWDCRDPKS
70 80 90 100 110 120
LVRPQKNEQP QEQNRYNSDF EKNHAKSARH IILIRHGEYL DVGDTDDTHH LTERGREQAK
130 140 150 160 170 180
FTGQRLHDLG IKWDKVIAST MVRAQETADI ILNEIDYDKA KVTNCAYLRE GAPIPPQPPV
190 200 210 220 230 240
GHWKPEASQF FRDGARIEAA FRRYFHRAYP DQTKESYTLI VGHGNVIRYF VCRALQFPPE
250 260 270 280 290
AWLRISINHA SITWLTISPS GNVSIKYLGD SGFMPVKHLT NRIPRDAKNV V