B4MYI5

PR
Gene name
GK22227
Protein name
Ribosome biogenesis protein BOP1 homolog
Names
Species
Drosophila willistoni (Fruit fly)
KEGG Pathway
dwi:6643324
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

18-136 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4MYI5

Entry ID Method Resolution Chain Position Source
AF-B4MYI5-F1 Predicted AlphaFoldDB

No variants for B4MYI5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4MYI5

No associated diseases with B4MYI5

8 regional properties for B4MYI5

Type Name Position InterPro Accession
repeat WD40 repeat 429 - 510 IPR001680-1
repeat WD40 repeat 555 - 597 IPR001680-2
repeat WD40 repeat 600 - 638 IPR001680-3
repeat WD40 repeat 641 - 680 IPR001680-4
repeat WD40 repeat 684 - 723 IPR001680-5
repeat WD40 repeat 735 - 778 IPR001680-6
domain BOP1, N-terminal domain 164 - 429 IPR012953
conserved_site WD40 repeat, conserved site 455 - 469 IPR019775

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
  • Nucleus, nucleoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
preribosome, large subunit precursor A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.

1 GO annotations of molecular function

Name Definition
ribonucleoprotein complex binding Binding to a complex of RNA and protein.

3 GO annotations of biological process

Name Definition
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
regulation of hemocyte proliferation Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKKQDRKRK VKDEATNDGA SGSDQSDNAE EEEDLLQTVK EPGEDSTDDE GIDQEYQSDS
70 80 90 100 110 120
SEDLEFESDE EGNYVGRKGG QQESSDEEEV DEEEEDDDDD DDEEEGGKVE DKPTTSSKAE
130 140 150 160 170 180
TNNEVAPLPA LPARDPSKQE YEDSDTSDEE DIRNTVGNIP MHWYDEYKHI GYDWDGNKII
190 200 210 220 230 240
KPIKGDQIDD FLRKIEDPDF WRTVKDPQTG QEVVLSDADI ALIKRINSAR IPNAEHEEYE
250 260 270 280 290 300
PWIEWFTSEV EKMPIKNVPD HKRSFLPSVS EKKRVSRMVH ALKMGWMKTT EEVEREKQQK
310 320 330 340 350 360
RGPKFYMLWE TDTGREQMRR IHDPVSAPKR DLPGHAESYN PPPEYLFDEK ETKQWLKLKD
370 380 390 400 410 420
EPHKRKLHFM PQKFKSLREV PAYSRYLRER FLRCLDLYLC PRAKRVKLNI DAEYLIPKLP
430 440 450 460 470 480
SPRDLQPFPT VESLVYRGHT DLVRSVSVEP KGEYMVSGSD DKTVKIWEIA TGRCIRTIET
490 500 510 520 530 540
EDVVRCVAWC PNAKLSIIAV ATGSRLLLVN PKVGDKLLIK KTDDLLAEEP SNQDIIDNER
550 560 570 580 590 600
IKTAVQWSTA EAAEQEKGVR VIINHFKPIR QVTWHGRGDY LATVMPEGAN RSALIHQLSK
610 620 630 640 650 660
RRSQIPFSKS KGLIQCVLFH PVKPCFFVAT QHNIRIYDLV KQELIKKLLT NSKWISGMSI
670 680 690 700 710 720
HPKGDNLLVS TYDKKMLWFD LDLSTKPYQT MRLHRNAVRS VAFHLRYPLF ASGSDDQAVI
730 740 750 760 770
VSHGMVYNDL LQNPLIVPLK KLQTHEKRDD FGVLDVCWHP VQPWVFSTGA DCTIRLYT