B4L6S9
Gene name |
Pgam5 |
Protein name |
Serine/threonine-protein phosphatase Pgam5, mitochondrial |
Names |
Phosphoglycerate mutase family member 5 homolog |
Species |
Drosophila mojavensis (Fruit fly) |
KEGG Pathway |
dmo:Dmoj_GI16420 |
EC number |
3.1.3.16: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B4L6S9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B4L6S9-F1 | Predicted | AlphaFoldDB |
No variants for B4L6S9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B4L6S9 | |||||
No associated diseases with B4L6S9
No regional properties for B4L6S9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for B4L6S9 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.16 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| myosin phosphatase activity | Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate. |
| phosphoprotein phosphatase activity | Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein dephosphorylation | The process of removing one or more phosphoric residues from a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRKFAAFACG | TGAGFAAYYF | QKLRDPLQVV | HNSWTNSERH | ISECALWDSN | WDYRDPKSLA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RPMKNDKPQE | QNRYNADLEK | NVSKYARHII | LIRHGEYLDV | GETDETHHLT | DRGRLQAKYT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GKRLHELGIK | WDKVIASNMV | RAQETAEIIL | NEIDFDKTKV | KSCSYLREGA | PIPPQPPVGH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WKPEASQFFR | DGARIEAAFR | RYFHRALPDQ | EKDSYTLIVG | HGNVIRYFVC | RALQFPAEGW |
| 250 | 260 | 270 | 280 | ||
| LRININHASI | TWLTISPSGN | VSIKYLGDTG | FIPAKHLTNR | IPREAKNVV |