B4HGK2
Gene name |
cav |
Protein name |
Telomere-binding protein cav |
Names |
Protein caravaggio |
Species |
Drosophila sechellia (Fruit fly) |
KEGG Pathway |
dse:6607705 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B4HGK2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B4HGK2-F1 | Predicted | AlphaFoldDB |
No variants for B4HGK2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B4HGK2 | |||||
No associated diseases with B4HGK2
14 regional properties for B4HGK2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain | 128 - 333 | IPR005479-1 |
| domain | Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain | 666 - 867 | IPR005479-2 |
| domain | Carbamoyl-phosphate synthetase, large subunit oligomerisation domain | 420 - 540 | IPR005480 |
| domain | Carbamoyl-phosphate synthase large subunit, CPSase domain | 19 - 33 | IPR005483-1 |
| domain | Carbamoyl-phosphate synthase large subunit, CPSase domain | 48 - 58 | IPR005483-2 |
| domain | Carbamoyl-phosphate synthase large subunit, CPSase domain | 168 - 180 | IPR005483-3 |
| domain | Carbamoyl-phosphate synthase large subunit, CPSase domain | 204 - 223 | IPR005483-4 |
| domain | Carbamoyl-phosphate synthase large subunit, CPSase domain | 239 - 256 | IPR005483-5 |
| domain | Carbamoyl-phosphate synthase large subunit, CPSase domain | 296 - 325 | IPR005483-6 |
| domain | Carbamoyl-phosphate synthase large subunit, CPSase domain | 378 - 396 | IPR005483-7 |
| domain | Methylglyoxal synthase-like domain | 930 - 1058 | IPR011607 |
| domain | ATP-grasp fold | 133 - 327 | IPR011761-1 |
| domain | ATP-grasp fold | 671 - 861 | IPR011761-2 |
| domain | Carbamoyl-phosphate synthase large chain, methylglyoxal synthase-like domain | 936 - 1046 | IPR033937 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromosome, centromeric region | The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| telomere cap complex | A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| telomeric DNA binding | Binding to a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| telomere capping | A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGTQMSAFL | RQYLADEDKK | IRAQFKESDP | NNKLILWMHE | KTRITEEDLA | RPYTEDEVKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LCLRTKVKVD | MTAWNCLWEA | KKRFEAKGRF | VNKSERFINR | MYVKAVRKKM | VQPYPEEFVA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QRREVVAAET | KKHNISRLDR | WQRKKTQNLS | AQESSPARGA | HLSFIDAMQT | HEDQVNANLS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SVSQINFQVE | AIARPAVSSS | DLSGIGDDED | EHQQSEFQDE | HINCPETAIN | ENSVRCDPIN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SGRMRTGCIN | SQGNNNTESD | PDYYMFGTQL | SSLLRPTSTQ | EPDDQVNCPE | TEMNESWVRC |
| 310 | 320 | 330 | |||
| DQINSESMSI | GPSIDSEGTI | TFQNSESEPI | DVDSIA |