Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B4HGE0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B4HGE0-F1 | Predicted | AlphaFoldDB |
No variants for B4HGE0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B4HGE0 | |||||
No associated diseases with B4HGE0
No regional properties for B4HGE0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for B4HGE0 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| Ndc80 complex | An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| meiotic metaphase plate congression | The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis. |
| meiotic spindle organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle. |
| mitotic metaphase plate congression | The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAIIMTESSY | ERRVKALYEK | QIRMEALEAK | FIKKVYKFNS | NLWDVKEAAC | RHQRKVGKLQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KVIMERREEL | DKRVSFIEEL | DRELEATKLR | SLAMKDRIKQ | QKMLARQRKN | EIMESIHTLS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KTTGTYINQE | ALPARVKGVT | VLRGDKRNQL | IPFDLKSTDV | EGLDSLCQHL | ESLNVDMAQW |
| 190 | 200 | 210 | 220 | ||
| QQLISLAMDV | AMESRAPTTP | PKEAANCNSI | IEIDLTSPTC | HI |