B4GXH4

PR
Gene name
wuho
Protein name
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho
Names
Species
Drosophila persimilis (Fruit fly)
KEGG Pathway
dpe:6598280
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

13-100 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4GXH4

Entry ID Method Resolution Chain Position Source
AF-B4GXH4-F1 Predicted AlphaFoldDB

No variants for B4GXH4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4GXH4

No associated diseases with B4GXH4

2 regional properties for B4GXH4

Type Name Position InterPro Accession
repeat WD40 repeat 153 - 193 IPR001680-1
repeat WD40 repeat 197 - 244 IPR001680-2

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Localized to the nuclei of nurse cells, follicle cells and oocytes at early stages, from germarium to stage 4 egg chambers
  • Also present in the nuclei of spermatocytes and in the apical cells of the testes
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
female germ cell nucleus The nucleus of the female germ cell, a reproductive cell in females.
male germ cell nucleus The nucleus of a male germ cell, a reproductive cell in males.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

4 GO annotations of biological process

Name Definition
oogenesis The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
RNA (guanine-N7)-methylation The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule.
spermatogenesis The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.
tRNA methylation The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATIFFAEPE LVIGHGRKVL FLNPGDLQIF KEIELPPDLT TCGLKTVEPV PAPGHPASSS
70 80 90 100 110 120
KQQPAALKEA TGSVKVEVSI QNVTYSPDRQ LLALTTAGQK AVLLYKSRPE NAQLLSIRPL
130 140 150 160 170 180
ARASSAPKVL QRWQLPFWSL TKREIAINTS VLRWMPRHVC FLGHLSIVYD VLWSEDQQYI
190 200 210 220 230 240
ITCDRDDKIR VTNYPATFDI HSYCLGHKEF VSGLAMLTEQ HIISASGDKT LRVWNYTCGK
250 260 270 280 290 300
ELLLHELPAP AVRMLVRQLE PEKTYEVAVL FYDYVDAIGV YRLEQTTTES WSITSTQLVR
310 320 330 340 350 360
AEAGTWNICN FALTDDRIYV TGAENERLTL RVYDSRNGER ASGLPEGWLK MVLDNLDVAA
370 380 390
FMPEDLSVWF KKRFDNVSDY LERKKRRIEE QKQQKCG