B4F2B9

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Proteus mirabilis (strain HI4320)
KEGG Pathway
pmr:PMI3418
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-442 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4F2B9

Entry ID Method Resolution Chain Position Source
AF-B4F2B9-F1 Predicted AlphaFoldDB

No variants for B4F2B9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4F2B9

No associated diseases with B4F2B9

8 regional properties for B4F2B9

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 415 - 584 IPR000795
domain Translation elongation factor EFTu-like, domain 2 836 - 903 IPR004161
domain Small GTP-binding protein domain 418 - 574 IPR005225
domain Translation initiation factor IF-2, N-terminal 5 - 47 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 339 - 389 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 59 - 97 IPR013575
domain Translation initiation factor IF- 2, domain 3 691 - 805 IPR023115
domain Translation initiation factor IF-2, domain II 591 - 684 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDETVKSLA EEIQTPVERL VQQFADAGIK KTVSDSVSQK EKETLLAWLN RDKESTSQPE
70 80 90 100 110 120
KLTLQRKVRS TLSVPGTGGK NKSVAIEVRK KRTYVNRDAV EKAQAAEQAQ REAEEKARRE
130 140 150 160 170 180
AEEKAQREAQ EKAQREAEEK AKREAEEAKK KAEEKAKREA EEAKREAAEL AKREAAEKDK
190 200 210 220 230 240
VKQNEKPKAD KADQEKARRI AEQAELKRKT EEAQRRKAEE EARIAAEKAR RLAEENAEKW
250 260 270 280 290 300
TSDTSSETEG TDYHVTTSRY ARDAEDESDA EVEGGRGRGR AAKAPRPKKN NRHSEKADRE
310 320 330 340 350 360
EARAAGRSNK KGKGRKNSTL QQGFNKPAAA VNRDVVIGET ISVADLANKM AVKGSEVIKT
370 380 390 400 410 420
MMKMGAMATI NQVLDQETAQ LVAEEMGHKV ILRRENELEE QVMNDRDTSD EMAVSRAPVV
430 440 450 460 470 480
TIMGHVDHGK TSLLDYIRST KVASGEAGGI TQHIGAYHVK TDKGEITFLD TPGHAAFTSM
490 500 510 520 530 540
RARGAQVTDI VVLVVAADDG VMPQTIEAIQ HAKAANVPVV VAVNKIDKPE ADPDRVKTEL
550 560 570 580 590 600
SQYGILPEDW GGETQFIHVS AKQGLGIDEL LDAILLQAEV LELKAVKEGM ASGVVIESYL
610 620 630 640 650 660
DKGRGPVATI LVREGTLNKG DIVLCGFEYG RIRAMRNELG KEVQSAGPSM PVEILGLSNV
670 680 690 700 710 720
PSAGDEATVV RDEKKAREVA LYRQGKFREV KLARQQKSKL ENMFANMEEG KVSELNIVLK
730 740 750 760 770 780
TDVQGTCEAI TDALVKLSTD EVKLKIIGSG VGGITETDAT LAAASDAIIL GFNVRADASA
790 800 810 820 830 840
RRIIEQESVD LRYYSVIYSL IDEIKSAMSG MLEPEYKQEI MGLAEVRDVF KSPKFGAIAG
850 860 870 880 890 900
CMVVEGNIKR NNPIRVLRDN VVIYEGELES LRRFKDDVNE VRNGMECGIG VKNYNDVRVG
910
DMIEVFQVIE IKRSID