B4F1L5

PR
Gene name
rsmB
Protein name
Ribosomal RNA small subunit methyltransferase B
Names
16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB
Species
Proteus mirabilis (strain HI4320)
KEGG Pathway
pmr:PMI3286
EC number
2.1.1.176: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-65 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4F1L5

Entry ID Method Resolution Chain Position Source
AF-B4F1L5-F1 Predicted AlphaFoldDB

No variants for B4F1L5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4F1L5

No associated diseases with B4F1L5

3 regional properties for B4F1L5

Type Name Position InterPro Accession
domain SAM-dependent methyltransferase RsmB/NOP2-type 164 - 422 IPR001678
domain NusB/RsmB/TIM44 7 - 127 IPR006027
conserved_site Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site 316 - 327 IPR018314

Functions

Description
EC Number 2.1.1.176 Methyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA (cytosine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine.

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTSYNLRSI AAKAIAQVLD QGLSLSSVIP ELQKNISDKD KALLQELCFG TLRTLPQLEW
70 80 90 100 110 120
IIQQLMDKPL KGKQRILHYL IMVGLYQLLY TRVPAHAALA ETVNGAIALK KPQLKGLING
130 140 150 160 170 180
VLRQFQRQQD VLMERFQNND SRYLHPSWLL TRIKNAYPEL WESIIEGNNQ KPPMWLRVNQ
190 200 210 220 230 240
IHHSREQYLA LLEKEGISAF SDDHHPNAIR LETPCNVHLL PGFNEGWVTV QDRSAQRCAE
250 260 270 280 290 300
LLAPQNNEQI LDLCAAPGGK TTHILEIAPK AHVLAIDIDE QRLARVKENL NRLKLHATVK
310 320 330 340 350 360
SGDGRYPEQW CANMQFDRIL LDAPCSATGV IRRHPDIKWL RRNEDIAQLA QIQKEILHAI
370 380 390 400 410 420
WPYLKSGGTL VYATCSILPE ENSQQIAAFL SSMQDAQCDY QHQCLPEQYS GDGFFYALIN
KK