B4EWI7

PR
Gene name
clsA
Protein name
Cardiolipin synthase A
Names
CL synthase
Species
Proteus mirabilis (strain HI4320)
KEGG Pathway
pmr:PMI1357
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

263-338 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4EWI7

Entry ID Method Resolution Chain Position Source
AF-B4EWI7-F1 Predicted AlphaFoldDB

No variants for B4EWI7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4EWI7

No associated diseases with B4EWI7

4 regional properties for B4EWI7

Type Name Position InterPro Accession
domain AAA+ ATPase domain 108 - 269 IPR003593
domain ATPase, AAA-type, core 109 - 305 IPR003959
domain Zinc finger, ClpX C4-type 1 - 54 IPR010603
domain Clp ATPase, C-terminal 311 - 405 IPR019489

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
cardiolipin synthase activity Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.

1 GO annotations of biological process

Name Definition
cardiolipin biosynthetic process The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTTFYTVLSW LTFFFYWLLI AGVTFRVLMH RRPVTSTMTW LLIIYILPLV GVIAYFAFGE
70 80 90 100 110 120
LHLGKRRVEH ARQMWPSVVA WLEELKKCKH IFAKHYSDVA EPIFQLTAKR QGINGVKGNK
130 140 150 160 170 180
IQLLTTCEDS LNAITRDINN ARDNIEMVFY IWQSGGLVEE VTEALIQAAK RGVKCRIMVD
190 200 210 220 230 240
SAGSRSFFRT NGPARMRAAG IEFVESLQVN LFRFFLRRMD LRQHRKIVLI DNYISYTGSM
250 260 270 280 290 300
NMVDPRYFKQ DAGVGQWIDI MVRMEGPVST TLGIIYAFDW EMETGERHLP PPPDNNIMPF
310 320 330 340 350 360
EQANGHTTQV IASGPGFPEE LIQQSLITAI YSARKELVMT TPYFVPSDDL AHAISTAAMR
370 380 390 400 410 420
GVDVSIIVPR SNDSFLVRWA SRAFFTEILE AGVKVFQFED GLLHTKSVMV DGQLSMVGSV
430 440 450 460 470 480
NLDMRSLWLN FEITVVIDDE CFASDLSIVQ YDYIARSTQL TLDEWEKRPF MNRVLERLCY
FFSPLL