B4EVS0

PR
Gene name
kdsA
Protein name
2-dehydro-3-deoxyphosphooctonate aldolase
Names
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase
Species
Proteus mirabilis (strain HI4320)
KEGG Pathway
pmr:PMI1090
EC number
2.5.1.55: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

68-137 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B4EVS0

Entry ID Method Resolution Chain Position Source
AF-B4EVS0-F1 Predicted AlphaFoldDB

No variants for B4EVS0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B4EVS0

No associated diseases with B4EVS0

1 regional properties for B4EVS0

Type Name Position InterPro Accession
domain DAHP synthetase I/KDSA 10 - 275 IPR006218

Functions

Description
EC Number 2.5.1.55 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
3-deoxy-8-phosphooctulonate synthase activity Catalysis of the reaction: D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H(+) + phosphate.

1 GO annotations of biological process

Name Definition
keto-3-deoxy-D-manno-octulosonic acid biosynthetic process The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQHKVVSIGD IKVANNLPFV LFGGMNVLES RDLAMRICEH YVTVTQKLDI PYVFKASFDK
70 80 90 100 110 120
ANRSSIHSYR GPGLDEGMKI FQELKETFGV KIITDVHEPS QAQPVSEVVD VIQLPAFLAR
130 140 150 160 170 180
QTDLVEAMAK TGAVINVKKP QFVSPGQMGN IVEKFKEGGN DQVILCDRGS NFGYDNLVVD
190 200 210 220 230 240
MLGFHVMMQA SEGAPVIFDV THSLQCRDPF GAASGGRRGQ VAELARAGMA VGLAGLFLEA
250 260 270 280
HPDPDHARCD GPSALPLAKL EPFLAQIKAI DSLVKSFPEL DTSK