B3WCM7

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Lacticaseibacillus casei (strain BL23) (Lactobacillus casei)
KEGG Pathway
lcb:LCABL_10420
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

536-628 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B3WCM7

Entry ID Method Resolution Chain Position Source
AF-B3WCM7-F1 Predicted AlphaFoldDB

No variants for B3WCM7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B3WCM7

No associated diseases with B3WCM7

9 regional properties for B3WCM7

Type Name Position InterPro Accession
domain Helicase, C-terminal 433 - 632 IPR001650
conserved_site SEC-C motif 892 - 909 IPR004027
domain SecA DEAD-like, N-terminal 6 - 398 IPR011115
domain SecA Wing/Scaffold 615 - 826 IPR011116
domain SecA, preprotein cross-linking domain 228 - 354 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 247 IPR014001
domain SecA motor DEAD 3 - 616 IPR014018
conserved_site SecA conserved site 496 - 511 IPR020937
domain SecA, C-terminal helicase domain 416 - 586 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MANILRKWVE SDKREIARLG KIADKVQQYE DEYAALSDEQ LKANTPKLKD RLAAGATLDD
70 80 90 100 110 120
ILPEAFATAR EGAKRVLGLF PFRVQIIGGI VLHEGNIAEM KTGEGKTLTA TMPVYLNALT
130 140 150 160 170 180
GKGVHVVTVN EYLSTRDATE MGELYNWLGL SVGLNLNSKN SDEKREAYNC DITYSTNSEL
190 200 210 220 230 240
GFDYLRDNMV VYKEQMVQRP LNFAIVDEVD SILIDEARTP LIISGGAEKT TGLYIRADRF
250 260 270 280 290 300
VKTLKAETDY KIDWPTKTIS LTESGIRKAE KNFGLDNLYD TENTALTHHI DQALRANYIM
310 320 330 340 350 360
LKDIDYMVSD GEVLIVDQFT GRAMEGRRYS DGLHQAIEAK EGVQIQDENK TMANITYQNF
370 380 390 400 410 420
FRMYTKLAGM TGTAKTEQEE FREIYNMEVI SVPTNKPVIR VDSPDVLYPT LDAKFNAVVE
430 440 450 460 470 480
DIKARHEKGQ PMLIGTVAIE SSERLSKQLD EAKIPHTVLN AKNHFKEAEI IMNAGQRGAV
490 500 510 520 530 540
TIATNMAGRG TDIKLGPGVT ELGGLAVIGT ERHESRRIDN QLRGRSGRQG DPGSTQFYLS
550 560 570 580 590 600
LEDDLMKRFG SDRIKAMLDR FKVADDDQVI QSRMISRQVE SAQKRVEGNN YDTRKNTLQY
610 620 630 640 650 660
DDVMREQREV IYKQRQQVIN EQETLKPVLM AMINRTITRI VQTHTQGDQK DWNLDALYAW
670 680 690 700 710 720
VTANMIDPEK FKRSQLDGKS QDELIGLLAE MAETNFQQKN KQLGDDAQML EFEKVVILRV
730 740 750 760 770 780
VDSAWTDHID AMDQLRQSIG LRGYGQMNPL VEYQEEGYRM FEEMIASIDD DVTRLFMKAE
IRQNIRR