B3RFC3

PR
Gene name
SERPINB10
Protein name
Serpin B10
Names
Species
Sorex araneus (Eurasian common shrew) (European shrew)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

29-119 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B3RFC3

Entry ID Method Resolution Chain Position Source
AF-B3RFC3-F1 Predicted AlphaFoldDB

No variants for B3RFC3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B3RFC3

No associated diseases with B3RFC3

2 regional properties for B3RFC3

Type Name Position InterPro Accession
conserved_site Serpin, conserved site 370 - 380 IPR023795
domain Serpin domain 7 - 397 IPR023796

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
serine-type endopeptidase inhibitor activity Binds to and stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSLANSINQ FALEFSKKLA ETDEGKNIFF SPWGISTTLA MVYLGTKGTT ATQMAQVLQF
70 80 90 100 110 120
DTDQDVKSSP ENEKKRKVDL NSDQVGEIHF GFQKLISEIN NPSNTYVLKT ANGIYGEKTY
130 140 150 160 170 180
PFHNKYIEDI KTYFGAKPQS VNFVEDSDQI RKDINSWVES QTEGKIPNLL PDDAVDSATK
190 200 210 220 230 240
MVLVNALYFK GLWEHQFSVQ DTTEKPFRIN KTSSKPVQMM SMKKNLEVFH IEKPQATGLR
250 260 270 280 290 300
LDYKNRDLSL LLILPEDVCG LDQLEKAITY DQLSEWTSED MMEMYTVELH LPKFKLEQSY
310 320 330 340 350 360
DLKTTLASMG MSDAFNQSKA DFSGMSDERN LYLSNVFHKS FVEINEQGTE AAAGSASEIS
370 380 390
VRIKLPTIEI NADHPFIFFI RHNKTNSILF YGRFCSP