B3QPY5

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum)
KEGG Pathway
cpc:Cpar_1590
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

781-863 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B3QPY5

Entry ID Method Resolution Chain Position Source
AF-B3QPY5-F1 Predicted AlphaFoldDB

No variants for B3QPY5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B3QPY5

No associated diseases with B3QPY5

5 regional properties for B3QPY5

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 621 - 810 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 13 - 124 IPR007695
domain DNA mismatch repair protein MutS, core 280 - 603 IPR007696
domain DNA mismatch repair protein MutS, connector domain 133 - 260 IPR007860
domain DNA mismatch repair protein MutS, clamp 440 - 530 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKSAQGRKK EPTPMMRQYL EVKERYPEYV LLFRVGDFYE TFLDDAVTVS AALNIVLTKR
70 80 90 100 110 120
SNGSAGEIPL AGFPHHASEG YIAKLVTKGF KVAVCDQVED PALAKGIVKR EITDIVTPGI
130 140 150 160 170 180
TYSDKILDDR HNNYLCAVAL FKRGREHLAG VAFVDVTTAE FRMTELPVAE LKDFLQSLHP
190 200 210 220 230 240
SEILISSRDK ELRDSLAKSM NTLFTVLDEW MFSAEQASQV LENHFKTHSL KGFGIDGVEG
250 260 270 280 290 300
GRIAAGAILQ YLEEAKQGSL KYLVRIGLVE SAETMTLDIQ TRRNLEIISS MQDGSLNGSL
310 320 330 340 350 360
LEVIDRTKNP MGARLLRRWL LHPLRKLEAV VQRHDAVEEL LESDSMREES RQLLGGIIDL
370 380 390 400 410 420
ERALARIATS RAMPREVRLL GSSFALIPQL KAMLASCEAQ RLRHLADRLD SLPELAETIE
430 440 450 460 470 480
RALDPEASGT LRDGGYIRAG YHEELDELRA ISSGARDRLL EIQQAERSKT SISTLKVQYN
490 500 510 520 530 540
KVFGYYIEVS RANSDKVPEY YEKKQTLVNA ERYTIPALKE YEEKILTAEE KSQFLEHRLF
550 560 570 580 590 600
QELCAAVAAE AASIQKTAAA LAELDCLACF ASCADEYRYC RPAMNEGTEL SITGGRHPVL
610 620 630 640 650 660
ERILGADEPY VANDCRVGSD QQLLIITGPN MAGKSSYLRQ AGLVVLLAQV GSFVPAESAE
670 680 690 700 710 720
IGLVDRIFTR VGASDNLTSG ESTFLVEMNE AASILNNATE RSLLLLDEIG RGTSTFDGMS
730 740 750 760 770 780
IAWSMCEFIH DRLRARTLFA THYHELAELE SRFERIVNFN ATVVETADTV IFLRKIVRGA
790 800 810 820 830 840
SDNSYGIEVA KMAGMPPEVI ERAREILAGM ERREVEVPTQ REAPPRVVSQ QISLFEEEES
850 860 870
RLRKALSGID INRLTPLDAM MELKRLQDIA LGKSKA