B3Q0S4

PR
Gene name
lysS
Protein name
Lysine--tRNA ligase
Names
Lysyl-tRNA synthetase, LysRS
Species
Rhizobium etli (strain CIAT 652)
KEGG Pathway
rec:RHECIAT_CH0003928
EC number
6.1.1.6: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

395-483 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B3Q0S4

Entry ID Method Resolution Chain Position Source
AF-B3Q0S4-F1 Predicted AlphaFoldDB

No variants for B3Q0S4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B3Q0S4

No associated diseases with B3Q0S4

3 regional properties for B3Q0S4

Type Name Position InterPro Accession
domain Haem peroxidase 92 - 713 IPR002016
binding_site Peroxidases heam-ligand binding site 262 - 272 IPR019793
active_site Peroxidase, active site 98 - 109 IPR019794

Functions

Description
EC Number 6.1.1.6 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
lysine-tRNA ligase activity Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).
magnesium ion binding Binding to a magnesium (Mg) ion.
nucleic acid binding Binding to a nucleic acid.

1 GO annotations of biological process

Name Definition
lysyl-tRNA aminoacylation The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADNKTENAL SSDATEVRAQ KLKLLREQIG DVYPAHFHRT MTNAELGAKY ESLEPDVETQ
70 80 90 100 110 120
DVVTVAGRVY SSRNSGMFMD IHDASGKIQI FSHKDVTGEE ARALLPMIDI GDIIGVTGVV
130 140 150 160 170 180
RRTKRGELTI NAQKIEMLTK SLLPMPEKWH GLSDIELRYR KRHLDIMTNE DSKLRFQQRS
190 200 210 220 230 240
KIVSGIRRFM ENDGFMEVET PMLQSIYGGA TAEPFKTHHN TLKLDMYLRI APELFLKRTL
250 260 270 280 290 300
VSGLTDKVFE INRNFRNEGV STRHNPEFTM MECYWAYADY EDMMDLVERL FEALALSIHG
310 320 330 340 350 360
TTEFDFGDKR LSFKGPFKRV PMPDAVKEAT GIDFLTIKTD EEARAAAKAA GFAVEKDWTW
370 380 390 400 410 420
GECLAFIFEE KVEATLIQPS HVTHFPKDIS PFAKEVPGEP RLVERFETYC NAWELGNAFS
430 440 450 460 470 480
ELNDPEEQRR RMVEQLEQAH ARGEKEKQLD EEFLDAIDQG MPPAGGLGIG VDRLIMLLTN
490
APSIRDVILF PARRNKAD