B3MNR6
Gene name |
hook |
Protein name |
Protein hook |
Names |
|
Species |
Drosophila ananassae (Fruit fly) |
KEGG Pathway |
dan:6498032 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B3MNR6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B3MNR6-F1 | Predicted | AlphaFoldDB |
No variants for B3MNR6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B3MNR6 | |||||
No associated diseases with B3MNR6
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| anchoring junction | A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. |
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| microtubule | Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. |
| synapse | The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| microtubule binding | Binding to a microtubule, a filament composed of tubulin monomers. |
| small GTPase binding | Binding to a small monomeric GTPase. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cytoplasmic microtubule organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. |
| cytoskeleton-dependent intracellular transport | The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. |
| determination of adult lifespan | The pathways that regulate the duration of the adult phase of the life-cycle of an animal. |
| endocytosis | A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSPKNEMYY | SLLEWFKTLN | LNAPHSDAES | LADGVALAQA | LNQFAPESFT | DGWLSKIKPG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AVGSNWRLRM | SNLKKVAQSV | YDYYSEVLNY | SLGDFAKPDV | QRIAEKCDLG | ELERLLQLVL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GCAVNCTNKQ | SYITEIMSLE | EELQANIMRA | LQELESTRNA | SSSPEAGGVV | SSLSRSSLSG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ILDGKALQEE | RDAMAQKCFE | TEKKMLLLID | EKTNLQQELQ | KLQQEVSRME | HSSTAIGDDG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VSLGPVQTGS | VRYNDLRRQL | DLLKEELLQS | EGAREDLKLK | AHQQETDLLH | MQIRIDELMK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SSAEVTTLKD | EVDVLRESND | KLKICEAQLD | TYKKKLEDYN | DLKKQVRILE | ERSADYVQQN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AQFEEDAKRY | ANTKGQVELF | KKEIQDLHAK | LDNESSKNVK | LEFDNKNLES | KNLALQRAKD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SLLKERDNLR | EVVDELKCGQ | LSSSSALAGN | TVSTELQPLA | TVDKLQRLEA | ENKALREGQG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GQTALAQLLD | EANKRNEHLR | EQLKTANERI | LSLSHATQSD | DPIFKENEFG | KQIKQLMELN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EQKTLQLEEA | VTQSSTMQCK | VTQLETNLAA | REQEILAYDA | KYRKCVEKAK | EVIKSIDPRI |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ASALDASVLE | KNAEVVEEEP | KPKMTVMEEQ | LMTSAFYRLG | VNAQRDAIDS | KLAILMGSGQ |
| 670 | 680 | ||||
| TFLARQRQSA | PRKSLSAMKS | K |