B3EUG6

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Amoebophilus asiaticus (strain 5a2)
KEGG Pathway
aas:Aasi_0139
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

25-353 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B3EUG6

Entry ID Method Resolution Chain Position Source
AF-B3EUG6-F1 Predicted AlphaFoldDB

No variants for B3EUG6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B3EUG6

No associated diseases with B3EUG6

5 regional properties for B3EUG6

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 407 - 577 IPR000795
domain Small GTP-binding protein domain 411 - 537 IPR005225
domain Translation initiation factor IF-2, N-terminal 333 - 382 IPR006847
domain Translation initiation factor IF- 2, domain 3 686 - 798 IPR023115
domain Translation initiation factor IF-2, domain II 583 - 678 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVEEKTIRLS QVARKLNVAT TTIAAYLLEK GFRVENKPNT KITLEQYKIL AEEFADSAMD
70 80 90 100 110 120
KEEAAELVIG QSYEKEPKVI AKQQEPIKHV HPKEKQVEIE KISLPVIDAP TIIEHKIIEH
130 140 150 160 170 180
KTEEPPILQP ELPTEEKEEL EVIESPQAPQ EELKPELETE VQEQDKEIQQ ELDDTAKVEQ
190 200 210 220 230 240
APITKGPEKI DFSKQGEFKG VTVLGKIELA EKKEPKKFQQ VASSDIDKKN KKRPRKRVAS
250 260 270 280 290 300
ETGLPSSGKR EEEANRYKPK GKVTNKTPEA PKTAVSEKQI QDQIKSTLAK LGGGKNVASR
310 320 330 340 350 360
AKYRREKRSL LAEEQAEERL QAAKDAKKLQ VTEFIAASDL ASLMGVSINQ LLSTCMNLGM
370 380 390 400 410 420
LVSINQRLDA EAITIIADEF GYQVAFTDVK TQELEEEEEA NPEDLVERAP IVTIMGHVDH
430 440 450 460 470 480
GKTSLLDYIR NTQITKTEAG GITQHIGAYE VVTESGKHIA FLDTPGHEAF TAMRARGAKL
490 500 510 520 530 540
TDIAIIVIAA DDGVRPQTKE AINHAKLAGV PIIIAINKMD KPQANPERVK EELAHLNILV
550 560 570 580 590 600
EDWGGKYQSQ GVSAISGEGV KELLEKILFE AELLELKANS HKKARGTVIE ASLDQGRGYL
610 620 630 640 650 660
ATIMVQDGNL RIGDVVLAGA YYGKIKAMFD YQGKPVKQAG PSTPMQILGL NGAPQAGDLF
670 680 690 700 710 720
RAMNTEKEAR DIATQRQQIL REQGFRTKTH ITLDEIGRRL AIGNFKELNI ILKGDVDGSV
730 740 750 760 770 780
EALSDSLLKL STEEIKVTIL HKGVGAIVES DILLAAASDA IIIGFQVRPT PPVRKLAEKE
790 800 810 820 830 840
GIEIRLYSII YDAINDIKDA MEGMLAPTIE EIITGSASVR EIFKITGTGT VAGCYVTEGY
850 860 870 880 890 900
IKKNNSIRVI RDGIVIYTGS IKHLKHFKEE MQQVKTGFEC GISITNFNDL KVNDVIEGFE
QKEVERKL