B3EP11

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Chlorobium phaeobacteroides (strain BS1)
KEGG Pathway
cpb:Cphamn1_0837
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

782-869 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B3EP11

Entry ID Method Resolution Chain Position Source
AF-B3EP11-F1 Predicted AlphaFoldDB

No variants for B3EP11

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B3EP11

No associated diseases with B3EP11

5 regional properties for B3EP11

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 623 - 812 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 13 - 124 IPR007695
domain DNA mismatch repair protein MutS, core 282 - 605 IPR007696
domain DNA mismatch repair protein MutS, connector domain 133 - 263 IPR007860
domain DNA mismatch repair protein MutS, clamp 442 - 532 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKVTPEKKKG SDTPMMRQYL EVKERYPEYL LLFRVGDFYE SFYEDARKVS EALNIVLTRR
70 80 90 100 110 120
SNGASADIPM AGFPHHACEG YIARLVKKGF KVTVCDQVED PSQAKGLVRR EITDIVTPGV
130 140 150 160 170 180
TYSDEILDDK HNNYLCALCF MKKGRERRAG VAFIDVTTAE FRIADLQPEQ VKDMLQSIQP
190 200 210 220 230 240
SEILLSSRDK SYSDTVSRIL PQEVVVTILD DWMFSEESAS QVIERHFKTH SLKGFGIDSA
250 260 270 280 290 300
FAARVAAGVV LHYLADTRQN RLQYITRIAL VDARDHMTLD LQTKRNLEII SSMQDGSTSG
310 320 330 340 350 360
SLLQVIDKTC NPMGARLLRR WLLRPLKRID AIQARLDAVE VLIEEGAVRK ALAEGLGGIH
370 380 390 400 410 420
DLERALSRIA TFRSMPREVR SLGSSLQKLP AIQALLKDSG SDRLKKLVSG LDLLDEITSI
430 440 450 460 470 480
IESAIDPEAG AKLRDGGYIR SGYNAELDLL RSVSSNAKSG LMEIQQAERR KTAISTLKIQ
490 500 510 520 530 540
YNRVFGYYIE VSKANSDKVP DYYEKKQTLV NAERYTIAEL KEYEVKILNA DEKSQMLEQE
550 560 570 580 590 600
LFRDLCVRIT ACSKEIQQNA EIVAELDCLH SYACCSEAYG YVKPEVKEHG NLSIKNGRHP
610 620 630 640 650 660
VLERILHVDE PYVPNDCFFD KKQRMLMVTG PNMAGKSSYL RQNGLIVLLA QVGCFVPADA
670 680 690 700 710 720
AEIGLVDRIF TRVGASDNLT SGESTFLVEM NEAANILNNA TGKSLILLDE IGRGTSTYDG
730 740 750 760 770 780
MSIAWAMSEY IQSVVGARTL FATHYHELAE LEERFDSISN YNATVVETAD KVVFLRKIVR
790 800 810 820 830 840
GASDNSYGIE VARMAGMPSE VIQRAKEILS GMEKRDIMIS FGKECAGTIE PQSRQIYLFE
850 860 870
EEERKLKNAI EALNINTMTP LDALLELKKL QDLAGGDG