B3BM80

PR
Gene name
cdiA4 (cdiA-CTo11, ECH7EC869_5883)
Protein name
Deoxyribonuclease CdiA-o11
Names
DNase CdiA, CdiA-o11-EC869, Toxin CdiA
Species
Escherichia coli O157:H7 (strain EC869)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

6-165 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for B3BM80

Entry ID Method Resolution Chain Position Source
4G6U X-ray 235 A A 88-377 PDB
4ZQW X-ray 200 A A/C 322-332 PDB
AF-B3BM80-F1 Predicted AlphaFoldDB

No variants for B3BM80

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B3BM80

No associated diseases with B3BM80

2 regional properties for B3BM80

Type Name Position InterPro Accession
domain AAA+ ATPase domain 51 - 207 IPR003593
domain Cdc6, C-terminal 294 - 382 IPR015163

Functions

Description
EC Number
Subcellular Localization
  • Target cell, target cell cytoplasm
  • Toxin translocation into the target cell depends on the proton motive force of the target cell, but not on tolA or tonB
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
deoxyribonuclease I activity Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.
metal ion binding Binding to a metal ion.
toxin activity Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVNATLSVVQ KNSAFVGSAT GELAARAIGM LYPGVKQSDL SEEQKQTIST LATVSAGLAG
70 80 90 100 110 120
GLTGSSTASA AVGAQSGKNA VENNYLSTNQ SLTFDKELSD CRKSGGNCQD IIDKWEKISD
130 140 150 160 170 180
EQSAEIDQKL KDNPLEAQVI DKEVAKGGYD MTQRPGWLGN IGVEVMTSDE AKAYVQKWNG
190 200 210 220 230 240
RDLTKIDVNS PEWTKFAVFA SDPENQAMLV SGGLLVKDIT KAAISFMSRN TATATVNASE
250 260 270 280 290 300
VGMQWGQGNM KQGMPWEDYV GKSLPADARL PKNFKIFDYY DGATKTATSV KSIDTQTMAK
310 320 330 340 350 360
LANPNQVYSS IKGNIDAAAK FKEYALSGRE LTSSMISNRE IQLAIPADTT KTQWAEINRA
370
IEYGKSQGVK VTVTQVK